Summary This open-label, first-in-human phase 1 dose-escalation trial evaluated the DNA vaccine pEVAC-PS, a computationally designed pan-sarbecovirus candidate delivered intradermally by needle-free PharmaJet Tropis in...
Summary In a NEJM Perspective, Victor Dzau and Laura DeStefano of the National Academy of Medicine (NAM) describe two public–private collaborations aimed at improving reliable health information on major digital...
Summary This global economic modeling study evaluated 50 years (1974–2024) of the WHO Expanded Programme on Immunization (EPI) across 194 WHO member states and 14 pathogens, using a societal-perspective cost model and...
Summary This retrospective single-center study (Guangyuan, China, September 2024–March 2025) linked clinical and BALF targeted-NGS pathogen data in 97 adults hospitalized with influenza-associated CAP. There were 51...
New Zealand — HPV schedule change takes effect From 27 July 2026, New Zealand’s school-based HPV program will shift to a single dose of Gardasil 9 with parental consent; dose 2 will still be free but will be...
Geneva/New York, July 15, 2026 — Global childhood immunization coverage edged higher in 2025, but progress remains fragile and uneven, with 13.5 million children receiving zero vaccine doses and measles outbreaks...
Summary This prospective case-control study enrolled 258 febrile inpatients and 48 controls at a rural Tanzanian hospital over one year (2023-2024), testing blood by PCR for 35 pathogens, culture, and serology. Measles...
Why We Need a Universal Influenza Vaccine Every year, millions of people roll up their sleeves for a flu shot, and every year, that same shot needs reformulating. This isn’t bureaucratic inefficiency — it’s...
Shigella vaccine breakthrough The live-attenuated oral Shigella sonnei vaccine WRSs2 reported 89% efficacy against shigellosis in a phase 2 controlled human infection trial — the highest protection rate ever recorded...