Download Infographic Overview This infographic provides an overview of tick-borne infectious diseases in humans, focusing on bacterial infections and babesiosis. It explains the relationship between causative...

1. MF59-aQIV looks economically persuasive in Korea and Taiwan — but the price assumptions do a lot of the work This modelling study assessed the cost-effectiveness of MF59-adjuvanted quadrivalent influenza...

World Immunization Week (24–30 April) has become the flagship moment each year when the global immunization community pauses, takes stock, and speaks with one voice about the power of vaccines. Each April, the...

Global vaccination policy this week feels less like harmonized orchestration and more like controlled fragmentation—with a purpose. European and Western Pacific advisory groups are quietly locking in 2026–2027...

Global WHO and public health WHO’s Technical Advisory Group on COVID-19 Vaccine Composition (TAG‑CO‑VAC) is preparing its next decision on updated COVID‑19 vaccine antigen composition, with a meeting scheduled...

Download Infographic Overview Tick-borne viral diseases are transmitted by infected ticks and occur across the globe. Clinical outcomes range from asymptomatic to mild febrile illness to severe disease...

1. Long COVID research needs patient peer review – not just patient quotes In a Lancet Infectious Diseases Comment, the authors argue that long COVID research systematically incorporates patient expertise via...

Download Infographic Overview Global vaccine production is estimated at approximately 14.5 billion doses annually. The global vaccine market reached around $35 billion in revenue in 2024–2025. Major global...

  Typhoid conjugate vaccine: primary target groups SAGE recommends introducing TCV in countries or settings with high or very high typhoid incidence, or with a substantial burden of antimicrobial...

1. RSV maternal vaccine vs infant immunization (Netherlands) Dutch researchers explored how pregnant women view the two new RSV prevention options for infants: a maternal RSV vaccine in pregnancy and an infant...

Global vaccine output remains highly concentrated among a few major producers. Here’s a snapshot of the latest estimates: (Note: Many companies do not publish per‑vaccine production figures; numbers marked...

Download Infographic Overview Lyme disease is a tick-borne infection caused by Borrelia burgdorferi sensu lato, transmitted through bites of infected Ixodes ticks. It typically begins with an expanding skin...

WHO kicks off World Immunization Week 2026 campaign messaging WHO has rolled out the 2026 World Immunization Week materials under a very on‑brand call to action: “Your decision makes a difference. Immunization...

In the first quarter of 2026, Vietnam experienced a marked resurgence of hand, foot and mouth disease (HFMD), with reported cases exceeding 25,000 and a concurrent increase in severe outcomes, including four...

Lyme borreliosis is a zoonotic tick-borne bacterial disease caused by several species within the Borrelia burgdorferi sensu lato complex, transmitted to humans by ticks of the Ixodes ricinus complex and...

Pfizer and Valneva announced topline Phase 3 VALOR data for their investigational 6‑valent OspA-based Lyme disease vaccine candidate PF‑07307405 (LB6V), reporting more than 70% efficacy in preventing Lyme...

Download Infographic Overview The concept of mRNA as a vaccine platform has evolved over several decades, using host cells to produce antigens. mRNA vaccines can induce both B cell and T cell immune responses...

Wild poliovirus (WPV1) Endemic transmission of WPV1 persists only in Afghanistan and Pakistan, which together form a single epidemiologic block.1-3 For 2025, WHO’s IHR Emergency Committee cites 40 WPV1 cases...

In 2021, surveillance systems in multiple countries detected a safety signal for myocarditis and pericarditis after mRNA COVID‑19 vaccination, particularly in adolescent and young adult males. Three years...

Global / Multicontinental COVID-19 vaccine myocarditis signal: updated interpretation CIDRAP summarises current evidence that the early myocarditis signal with mRNA COVID-19 vaccines in young males was real...

After years of disappointments, the C. difficile vaccine field is quietly repositioning itself. While GSK has officially dropped its own toxoid candidate from the pipeline, at least two other toxin‑based...

Brazil develops and rolls out single-dose dengue vaccine This article signals a major advance toward operationally feasible dengue vaccination, especially in high-burden, access constrained settings, and may...

Download Infographic Overview Classical vaccine manufacturing is a structured 5-step process that transforms a biological seed into a safe, injectable vaccine. It begins with antigen production, where microbes...

Broad Immunity from Naturally Occurring Influenza Antibodies The findings indicate that broadly neutralizing human antibodies can target conserved epitopes in the HA head, not just the stem, broadening the...

EMA backs first mRNA flu–COVID combination vaccine for older adults The EMA’s CHMP has issued a positive opinion for Moderna’s mRNA combination vaccine “mCombriax,” targeting both seasonal influenza and...

Download Infographic Overview Whole-cell Pertussis & Brain Damage: No causal link exists; earlier associations were actually coincidental onsets of inherited conditions like Dravet syndrome. Measles/MMR...

Artificial intelligence is rapidly reshaping the life sciences industry. From protein structure prediction to automated clinical documentation, AI systems are beginning to influence nearly every stage of...

The trajectory of vaccine development in high‑income countries is approaching a turning point. With the licensure of respiratory syncytial virus (RSV) vaccines and monoclonal antibodies, most high‑incidence...

Download Infographic Overview An adverse event (AE) is any medical event occurring after vaccination, regardless of whether it is causally related. A side effect is a medical event that is confirmed to be...

The Lancet has spoken when a leading medical journal titles an editorial “Robert F Kennedy Jr: 1 year of failure,” the experiment in anti‑expert governance is clearly not going well. RFK Jr arrived at HHS...

Regulatory, policy, and manufacturer news WHO influenza vaccine composition: WHO issued its recommendations for the 2026–2027 Northern Hemisphere seasonal influenza vaccine composition on 26 February 2026...

Introduction When it comes to vaccines and vaccination, nothing worries patients more than potential side effects. The fear that vaccination could lead to death or disability dates back to the time of Jenner...

Download Infographic Overview Maternal vaccination is a core component of life-course immunization and provides passive antibody protection to infants during the first six months of life through transplacental...

An article in The New York Times describes a coordinated national campaign by allies of Robert F. Kennedy Jr., the US Secretary of Health and Human Services, to roll back long-standing vaccine mandates for...

Vaccination in pregnancy has quietly become one of the most powerful tools we have to protect both mothers and their infants in the first months of life. During this period, infants are highly vulnerable to...

Download Infographic Overview This infographic is designed to help readers think critically about whether vaccination against specific vaccine-preventable diseases is appropriate for them. It encourages...

(for readers who believe precision is not pedantry — it’s public service) It’s a truth universally acknowledged that English‑language vaccine papers are often written by those who do not think in English — and...

Respiratory syncytial virus (RSV) is an enveloped, negative-sense, single-stranded RNA pneumovirus with 2 key surface glycoproteins, the fusion (F) protein and the attachment (G) protein, which are the...

Download Infographic Overview Encourages individuals to assess their risk of exposure to a specific disease before deciding on vaccination. Explains how to weigh disease risks against vaccine risks and...

The January 2025 GNN monthly update reports on key NITAG and GNN activities and selected new recommendations in immunization policy. It notes the postponement of the planned in‑person GNN meeting in April 2025...

Overview The past week brought important signals on continental immunization strategies (Africa), local manufacturing (South Africa, India), next generation COVID-19 and mucosal vaccines (Europe...

As the world reaches the midpoint of the Immunization Agenda 2030 (IA2030), immunization programs find themselves at an inflection point.1 The initial focus on recovering from pandemic-era backsliding is...

Download Infographic Overview Climate change and increased human mobility are altering the risk patterns of vaccine-preventable diseases (VPDs). Rising temperatures, changing rainfall, and extreme weather...

North America – Politics First, Evidence Second US vaccine policy spent the week in committee rooms and courtrooms, as reforms to ACIP processes and federal advisory structures drew fire from professional...

“Shared decision‑making” sounds benign, even progressive. Who would object to clinicians and families talking through risks and benefits together? Yet as it is currently being applied to vaccination, “shared...

Download Infographic Overview Vaccine development starts by assessing unmet medical need, often with limited epidemiological data. A Target Product Profile (TPP) defines key vaccine characteristics and guides...

What is EUVABECO? The EUVABECO project — short for European Vaccination Beyond COVID-19 — is a major initiative funded under the EU4Health programme, aiming to translate lessons from the COVID-19 pandemic into...

The processes around vaccine licensure today are still built on a shared core: robust evidence for quality, safety, and efficacy, demonstrated through standardized preclinical testing, phased clinical trials...

Europe kicked off 2026 by adding more brains to the vaccine bureaucracy, designating a new WHO Collaborating Centre to help NITAGs turn messy evidence into cleaner policy decisions. In theory, this means fewer...

Download Infographic Overview This infographic shows how vaccines help fight antimicrobial resistance (AMR) by preventing infections before antibiotics are needed. It presents a simple causal chain: fewer...

Evidence from leading journals since 2021 consistently documents both pronounced vaccine inequity between countries and substantial within‑country access gaps, especially for COVID‑19 but also for routine...

In the last days, there have been notable developments in COVID‑19 vaccine formulations, WHO prequalification, and – as reported before – politically driven schedule changes in the US. ​ Very...

Download Infographic Overview Vaccines contain active ingredients (antigens; mRNA) and inactive ingredients such as stabilizers, antimicrobials, inactivating agents, antibiotics, and residues from the...

WHO’s vaccination work represents one of the clearest examples of sustained, science‑based global cooperation in public health, and the attached summary illustrates how far‑reaching and internally coherent...

Download Infographic Overview Historical background: Combination vaccines have been used since 1945, beginning with the trivalent influenza vaccine. Vaccine composition: They combine either different serotypes...

In short: Classic vaccines have picked most of the low-hanging fruit: stable-antigen pathogens tamed by robust neutralizing antibodies, leaving the real fun to TB, HIV and other shape-shifters that demand...

Europe  On 11 December 2025, EMA’s CHMP recommended granting marketing authorisation in the EU for mNexspike, an mRNA COVID-19 vaccine targeting the LP.8.1 variant for the 2025–26 season, adding another option...

There are moments when recognition feels less like an achievement and more like a quiet affirmation – a reminder of why the journey began, and why it continues. For me, health literacy has always been...

Download Infographic Overview Pregnancy: Includes Tdap, Influenza, COVID-19, and RSV. Infants and Toddlers (29 vaccines): A comprehensive list featuring DTaP-Hib-IPV, HBV, PCV, Rotavirus, Influenza, MenACWY...

We are aware of two vaccines in late clinical development (Phase 2 completed) globally to address a significant medical need for pregnant women and their offspring, one from Pfizer in the United States and one...

In the wake of the COVID19 pandemic and the evolution of mRNA vaccines, the global vaccine industry in 2025 is characterized by rapid expansion of manufacturing capacity, especially for mRNA and other novel...

Download Infographic Overview A live attenuated vaccine against varicella (later also used to prevent zoster) was developed in 1974 by Takahashi and colleagues. The varicella vaccine was licensed for universal...

Question: I received Zostavax 10 years ago. Can I now get vaccinated with Shingrix? Answer: Yes. The Evidence. The study referenced below shows that the Shingrix is immunogenic and well-tolerated in older...

The World Health Organization provides a detailed report on the Ebola virus disease (EVD) outbreak that occurred in the Bulape Health Zone of Kasai Province, Democratic Republic of the Congo (DRC), in 2025...

In a NEJM Perspective, 12 former FDA commissioners warn that new internal FDA directives on vaccine regulation threaten evidence‑based policy, innovation, and public health. The piece responds to a memo by the...

Download Infographic Overview Infectious diseases (ID) are a major cause of morbidity and mortality in immunocompromised hosts (ICH). IDs may also trigger underlying conditions, graft-versus-host disease...

Critical Summary This article evaluates the cost-effectiveness of recently available respiratory syncytial virus (RSV) immunization options—nirsevimab (a long-acting monoclonal antibody) and the maternal...

Critical Summary The article by Malkin et al. presents the results of a phase 1, double-blind, randomized clinical trial evaluating the safety and immunogenicity of the rVSVΔG-LASV-GPC vaccine, a recombinant...

This narrative review by Gromer et al. provides a comprehensive synthesis of the long-observed but poorly characterized relationship between vaccine reactogenicity—short-term, inflammatory adverse events—and...

The 2025 study by Bui and colleagues reports on active, periodic surveillance of influenza A viruses (AIVs) at live bird markets (LBMs) in northern Vietnam — a region and context recognized as high-risk for...

Western Companies Pfizer updated its public R&D pipeline on 4 November 2025, highlighting late-stage vaccine assets (including RSV, meningococcal, and next-generation COVID products) while signaling a more...

Marburg virus disease – Ethiopia (first recorded national outbreak) Marburg is a filovirus causing severe hemorrhagic fever with high case fatality; Ethiopia’s first outbreak in South Ethiopia Region has led...

This article presents a large-scale, longitudinal analysis of symptom patterns and the perceived disease burden of COVID-19 in the Netherlands, covering a 4.5-year period from November 2020 to April 2025...

Health Secretary Kennedy’s new policy direction on vaccines centers on undermining CDC assurances about vaccine safety (especially regarding autism and aluminum adjuvants) and on opening the door to schedule...

Download Infographic Overview Vaccines are biological preparations, often made from attenuated or killed forms of microorganisms or fractions thereof. They work by stimulating the immune system to produce...

As one of the most prominent expert on polio, Jacob John and his colleagues write, vaccine safety is usually defined as the absence of serious adverse events in the vaccine recipient, yet the continued use of...

The first modern Lyme vaccine, LYMErix, was an OspA-based recombinant subunit vaccine that showed good efficacy and acceptable safety in phase III trials but ultimately failed due to a confluence of...

For many years, the CDC’s vaccine-safety pages stated clearly that vaccines do not cause autism and used that phrase as a concise summary of a large evidence base. The earlier material explained that multiple...

Kyasanur Forest Disease (KFD) is a neglected, tick‑borne viral haemorrhagic fever of the Western Ghats (India) that has expanded geographically since its first recognition in 1957 in Shimoga district...

Download Infographic Overview Vaccinations are among the most effective and cost-effective means to reduce the burden of serious infectious diseases. As vaccination rates remain too low to realize the full...

Summary This perspective explores the unprecedented political and administrative attack on harm reduction in the United States during 2025. Defined not by bureaucracy but by a set of evidence-based practices...

Summary This analysis provides a comprehensive estimate of the future global lives saved through vaccination, modeling the projected mortality benefits if all countries achieve high coverage for 14 key vaccine...

Summary This study evaluates the effectiveness of seasonal influenza vaccination in California by analyzing data from mandatory statewide public health reporting systems for influenza laboratory results and...

Download Infographic Overview Vaccines must meet the highest standards for safety and efficacy, as they are used for the prevention of diseases in healthy subjects, not as treatment for disease. Vaccines are...

The Influenza vaccination After Myocardial Infarction (IAMI) trial is a pivotal, multicenter, randomized, double-blind, placebo-controlled study designed to assess the clinical benefit and safety of influenza...

Using an innovative study design, Fröbert et al. report that influenza vaccination within 72 hours of hospital admission for myocardial infarction significantly reduced all-cause and cardiovascular mortality...

Several major global vaccine manufacturers released updates and company news since October 25, 2025, spanning Western, Asian, and  African producers. Western Producers Dynavax Technologies (USA): Reported...

Download Infographic Overview HPV (Human Papillomavirus) is extremely common worldwide and is mainly transmitted through sexual contact; most people are infected shortly after the onset of sexual activity...

SummaryThis comprehensive systematic review by leading US researchers, published in the New England Journal of Medicine, synthesizes new evidence on the effectiveness and safety of COVID-19, RSV, and influenza...

The October 2025 issue of POLIO NEWS underscores the urgent global need for polio eradication and highlights how ongoing outbreaks, regional collaboration, and donor support remain pivotal to the effort. Key...

Download Infographic Overview Meningococcal disease is caused by the Gram-negative bacterium Neisseria meningitidis (the meningococcus). It remains a significant public health issue globally, causing both...

The article presents an extensive global analysis of the introduction, establishment, and spread of non-native mosquito species implicated in human disease transmission, with direct implications for clinical...

Western Companies Moderna announced topline results from a Phase 3 pivotal trial evaluating mRNA-1647, an investigational cytomegalovirus (CMV) vaccine. The study did not meet its primary efficacy endpoint of...

Overview Recent surveillance data from Cambodia reveal a concerning resurgence of zoonotic human infections with highly pathogenic avian influenza (HPAI) H5N1 after more than a decade of apparent absence...

As presented in a recent Vaccelerate webinar, researchers at the University Hospital Cologne represent a major advancement in population-based infectious disease surveillance. Conducted over 12 months and...

Download Infographic Overview Like measles, mumps is caused by a paramyxovirus and affects only humans. The word “mumps” may relate to an old English term meaning grimace or mumble. Mumps was first...

Mumps virus infection can impair fertility in both sexes, though permanent sterility occurs far less frequently than transient testicular or ovarian inflammation. In post-pubertal males, mumps orchitis remains...

Background Post-acute sequelae of SARS-CoV-2 infection (PASC), commonly termed “long COVID,” continue to impose significant burdens on affected individuals and healthcare systems. While previous studies have...

October 18 2025 – Pfizer Inc. reported strong global engagement ahead of IDWeek 2025 in Atlanta, where the company presented findings from 46 clinical and real-world vaccine studies covering COVID-19, RSV...