Global Health Press

Discovery of new Covid infection mechanism offers clue to SARS-CoV-2 leap to humans

One of the best-known aspects of the Covid-19 pandemic is that the virus ‘jumped’ into people from animals – perhaps bats or pangolins – in a process known as zoonotic transfer. What hasn’t been clear to...

Global Health Cast Edition 3

Third Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. Topics Covered: 00:00 Introduction 01:00 COVID-19 update and news 05:08 Can scientists/physicians make a difference in...

Down-regulating TAO2 prevents influenza from replicating in cells and could provide new target for antiviral therapies

A collaborative study from UT Southwestern scientists has identified a new function for a protein called TAO2 that appears to be key to inhibiting replication of the influenza virus, which sickens millions of...

Women more likely to have long COVID, different symptom profile

Women are significantly more likely than men to experience long COVID, with symptoms that follow a distinct clinical pattern, researchers reported. They said more efforts are needed to explore sex differences...

Understanding poor vaccine responses in individuals with weakened immune systems

When the COVID-19 vaccine first became available, people eagerly signed up for coveted slots to boost their antibodies against the virus that shut down much of the world. But not everyone who rolled up their...

Emory participating in trial to test mRNA HIV vaccine in humans

Emory University is participating in a Phase I clinical trial to evaluate the use of messenger RNA (mRNA) technology in HIV vaccines for the first time in humans. The trial, IAVI G002, was launched earlier...

Global Health Cast Edition 2

Topics Covered: 00:00 – Introduction 00:55 – Global COVID-19 situation: cases continue to decline 05:26 – AZD7442 – mAB for prevention of COVID-19 09:12 – Lack of Immune response to...

Going all the way: Scientists prove inhaled vaccines offer better protection than nasal sprays

Inhaled aerosol vaccines provide far better protection and stronger immunity than nasal sprays, McMaster scientists who compared respiratory vaccine-delivery systems have confirmed. While nasal sprays reach...

Monkeypox DNA hints virus has been spreading in people for years

Genome sequencing confirms that monkeypox cases outside Africa are all related and suggests the virus responsible may have been circulating in people since 2017 Rather than jumping to humans from animals...

Respiratory virus ‘kills 100,000 children under five’

Respiratory syncytial virus (RSV) is common cause of infections such as pneumonia. Most cases and deaths in young children occur in lower-income countries. Passive immunisation campaign urged for babies under...

As monkeypox threat grows, scientists debate best vaccine strategy

Favored shot is a seemingly safer smallpox vaccine, but efficacy remains unclear In 1959, German microbiologist Anton Mayr took a strain of vaccinia, a poxvirus used to inoculate against smallpox, and started...

Legionellosis Outbreak in New York City

The number of Legionnaires’ disease cases has increased from 19 to 24, and the death toll has risen from 1 to 2, the New York City health department said on June 1st, 2022. Four people are currently...

No more flu for you? Discovery blocks influenza virus’ replication in cells

SUMOylation inhibitor could lead to highly effective ways to treat the flu and other respiratory viruses It happens every year, especially in winter. A virus saunters into your wide-open respiratory tract...

Real-time, accurate virus detection method could help fight next pandemic

A method of highly accurate and sensitive virus identification using Raman spectroscopy, a portable virus capture device and machine learning could enable real-time virus detection and identification to help...

International study reveals factors contributing to COVID-19 vaccine hesitancy among healthcare providers

A new 23-country study by a multidisciplinary team of researchers in the journal Vaccine, published by Elsevier, sheds light on the factors that contribute to COVID-19 vaccine hesitancy among healthcare...

New type of pneumococcal vaccine developed by KI scientists

Researchers at Karolinska Institutet have identified a new vaccine candidate against pneumococci, bacteria that can cause pneumonia, sepsis, and meningitis. The vaccine molecules comprise nano-sized membrane...

How COVID-19 created dramatic changes in a ‘winter virus’

The pandemic is changing the genetic landscape of virus strains A University of Sydney- led study reveals how the pandemic has changed the normal patterns of winter viruses in Australia, with new strains...

Viruses that were on hiatus during Covid are back — and behaving in unexpected ways

For nearly two years, as the Covid pandemic disrupted life around the globe, other infectious diseases were in retreat. Now, as the world rapidly dismantles the measures put in place to slow spread of Covid...

China’s hope for homegrown mRNA vaccine holds back nation

China has not been using the kind of COVID-19 vaccine that has proven to offer the best protection against the virus. The country is working through its biggest coronavirus outbreak yet without a tool it could...

Are we doing enough to prevent future pandemics?

Damage to our climate, shifting patterns of animal and human interaction, urbanization, the creep of antimicrobial resistance (AMR) and increased international trade and travel are all creating more...

Confirmed monkeypox case in North America

Scientists at the Centers for Disease Control and Prevention (CDC) are collaborating with the Massachusetts Department of Public Health to investigate a case of monkeypox in a Massachusetts resident who had...

Smallpox vaccine, IMVANEX, to be supplied to unknown European country in response to monkeypox

Bavarian Nordic A/S announced Thursday that the Company has secured a contract with an undisclosed European country to supply its IMVANEX® smallpox vaccine in response to new cases of monkeypox evolving during...

mRNA HIV vaccine candidate launches first-in-Africa study

The nonprofit scientific research organization IAVI and Massachusetts-based Moderna, Inc. recently announced that a Phase I clinical trial of an mRNA HIV vaccine antigen (mRNA-1644) will soon launch at the...

Smallpox vaccines can be 85% effective against monkeypox: WHO

Data shows that vaccines that were used to eradicate smallpox are up to 85 percent effective against monkeypox, according to the World Health Organization (WHO). There isn’t a specific vaccine for...

The World Vaccine Day – GHP-Symposium

 Keynote Speakers Time Topic Presenter 1:00pm Opening: GHP website Prof. Dr. Heinz Josef-Schmitt Mainz, Germany 1:05pm COVID Summary (45 mins) Prof. Robert Booy Sydney, Australia 1:50pm Measles Elimination...

Why is the 100-year-old BCG vaccine so broadly protective in newborns?

The century-old Bacille Calmette-Guérin (BCG) vaccine against tuberculosis is one of the world’s oldest and most widely used vaccines, used to immunize 100 million newborns every year. Given in countries with...

Climate change will force new animal encounters — and boost viral outbreaks

Over the next 50 years, climate change could drive over 15,000 new cases of mammals transmitting viruses to other mammals, according to a study published in Nature. It’s one of the first to predict how global...

Vaccine-preventable disease outbreaks on the rise in Africa

Brazzaville – Africa is witnessing a surge in outbreaks of vaccine-preventable diseases over the past year. Almost 17,500 cases of measles were recorded in the African region between January and March 2022...

Omicron less severe than Delta but more easily evades boosters

Three new observational studies from Scotland, Denmark, and the United States detail reduced hospitalizations and emergency department (ED) visits for Omicron COVID-19 infections relative to those caused by...

Multi-Country – Acute, severe hepatitis of unknown origin in children

Outbreak at a glance: Since the WHO Disease Outbreak News on Acute hepatitis of unknown etiology – the United Kingdom of Great Britain and Northern Ireland was published on 15 April 2022, there have been...

Population-wide study of COVID-19 vaccination shows that mix-and-match approach to booster vaccination offers the best protection

A new study on Chile’s national COVID-19 vaccination program, to be presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2022, Lisbon 23-26), and published in...

New Ebola outbreak declared in the Democratic Republic of Congo

The health authorities of the African nation declared a new outbreak of Ebola after a case was confirmed in Mbandaka, a city in the north-western Equateur Province, the World Health Organization (WHO) reported...

Effect of 13-valent pneumococcal conjugate vaccine on hospitalization in older adults

Invasive pneumococcal disease rates have decreased substantially in children and adults since 2010, when use of 13-valent pneumococcal conjugate vaccine in children became the standard of care. Adults 65 years...

Smartwatches and fitness bands reveal individual physiological responses to COVID-19 vaccine

A new digital health study by researchers at Scripps Research shows how data from wearable sensors, such as smartwatches and fitness bands, can track a person’s physiological response to the COVID-19...

Ebola virus hides out in brain

Monkeys treated with monoclonal antibodies fully recovered, but infection recurred The Ebola virus can hide in the brains of monkeys that have recovered after medical treatment without causing symptoms and...

Experts warn of possible XE subvariant outbreak in Japan

Public health experts have warned of a possible outbreak of the XE subvariant of the omicron coronavirus variant in Japan, where signs of a potential seventh COVID-19 wave are emerging. The health ministry...

Europe on alert as UK investigates mysterious cases of severe hepatitis in young children

The World Health Organization (WHO) and the EU’s health agency have issued warnings to other countries to be on the alert following a mysterious spike in cases of severe liver disease in children in the UK...

Why US-Universities Battle Meningitis Outbreaks

The CDC issued a health warning on April 9, 2022 about an outbreak of meningococcal disease in Florida. Multiple meningococcal disease cases in college students had been reported in the state of Florida over...

New findings show effectiveness of meningococcal B vaccine against gonorrhoea

Researchers at The University of Adelaide have found that the meningococcal B vaccine could improve protection against gonorrhoea in addition to protection against meningococcal B meningitis. This significant...

Case of probable transmission of tick-borne encephalitis virus from an unvaccinated mother to an infant through breast-feeding

A recent study published in Emerging Infectious Diseases discusses a case report of the probable vertical transmission of tick-borne encephalitis virus (TBEV) from an unvaccinated mother to her newborn via...

New study from UCI reveals how to rejuvenate the immune system of elderly people and reduce their risk of infectious disease

A new study, led by researchers from the University of California, Irvine, identifies a reason for why older adults are significantly more susceptible to infectious diseases than younger people, a critical...

One-dose Human Papillomavirus (HPV) vaccine offers solid protection against cervical cancer

The 4-7 April convening of the WHO Strategic Advisory Group of Experts on Immunization (SAGE) evaluated the evidence that has been emerging over past years that single-dose schedules provide comparable...

Deciphering insect-borne viruses

There is no treatment or vaccine for the West Nile, dengue, or Zika viruses. These infections caused by flaviviruses—mosquito-borne viruses—are a major public health concern worldwide. Understanding their...

IU awarded $1.2M to develop first-of-its-kind rotavirus-norovirus vaccine for infants

Indiana University will further develop a new technology for a combination oral rotavirus-norovirus vaccine for infants, thanks to a $1.2 million grant from venture capital firm GIVAX Inc. The technology...

ECDC and EMA issue advice on fourth doses of mRNA COVID-19 vaccines

The European Centre for Disease Prevention and Control (ECDC) and EMA’s COVID-19 task force (ETF) have concluded that it is too early to consider using a fourth dose of mRNA COVID-19 vaccines (Pfizer’s...

Vaccelerate: EU-Commission funded academic consortium to speed up vaccine development

The COVID pandemic showed lack of preparedness in many public health areas all over Europe. One such gap – often overlooked – is the lack of tools to rapidly conduct clinical studies on new vaccines...

A spotlight on avian influenza

Behind geopolitical conflicts and the ongoing COVID-19 pandemic are the sporadic chains of avian influenza outbreaks with 79 notifications spread across countries from Africa, Asia, Europe and America within...

Pfizer, Moderna vaccines aren’t the same; study finds antibody differences

The mRNA-based COVID-19 vaccines made by Pfizer/BioNTech and Moderna have proven highly effective at priming our immune systems to fight the pandemic coronavirus—preventing substantial amounts of infection...

TBE virus infection without central nervous system involvement

Background Most TBE virus infections remain asymptomatic; but when the infection is symptomatic, the disease can manifest with fever and can often involve the central nervous system (CNS) which leads to tick...

Japan disease institute says that aerosol transmission could lead to COVID infection

Japan’s National Institute of Infectious Diseases (NIID) announced on its website on March 28 that the coronavirus can be transmitted through inhalation of aerosols floating in the air containing the...

Noma, a neglected tropical disease?

Noma is also known as necrotizing ulcerative stomatitis or cancrum oris, a severely debilitating orofacial infection. It has been known for centuries and was already reported by Hippocrates and other...

Test can predict severe dengue infection, study finds

Researchers have created a test that can predict which dengue patients will likely have mild symptoms and which should be clinically monitored for a high risk of severe illness. Most of the about 390 million...

NUS-Monash University collaboration produces universal flu vaccine candidate

Influenza, commonly referred to as “flu”, is a major global public health concern and a huge economic burden to societies. Seasonal influenza epidemics afflict between 13 to 100 million individuals annually...

Vaccine-induced T cells provide long-lasting immune response to COVID-19: study

The human body’s T cells provide long-lasting memory against the virus following vaccination or infection from COVID-19, a study led by the Peter Doherty Institute for Infection and Immunity (Doherty...

How dangerous is BA.2, the new COVID-19 variant?

As COVID-19 case numbers climb in East Asia and now Europe — a surge largely attributed to the BA.2 subvariant of omicron — it makes sense that concern would rise in the U.S. It’s happened before during the...

Pertussis outbreak in indigenous population in Colombia

A Bordetella pertussis outbreak has been reported by the National Institute of Health (INS) of Colombia in the Kogui community, an indigenous group living in the Sierra Nevada de Santa Marta mountains in...

Nanoparticle-based COVID-19 vaccine could target future infectious diseases

Just one dose of a new nanoparticle-based COVID-19 vaccine was enough to produce an immune response in animals on track with vaccines currently in clinical use. And with minor changes, Northwestern University...

Effectiveness of antibiotics significantly reduced when multiple bugs present

A study has found that much higher doses of antibiotics are needed to eliminate a bacterial infection of the airways when other microbes are present. It helps explain why respiratory infections often persist...

Kenya takes a strong stand in Covid-19 vaccinations to minimize the spread of the disease

Kenya identified its first case of Covid-19 on 12th March 2020. It has since then undertaken a series of measures to contain the spread and management of the disease in the country. In a population of...

New modelling framework developed to improve infectious disease control

A new model to analyse infectious disease outbreak data has been developed by mathematicians that could be used to improve disease tracking and control. Researchers from the University of Nottingham developed...

New study confirms bioengineered RSV protein vaccine evokes protective immune response

Close interactions with infectious disease set both UC Santa Cruz graduate student Ana Nuñez Castrejon and Associate Professor of Biomolecular Engineering Rebecca DuBois on the path of studying respiratory...

Nosocomial Mycobacterioides chelonae Outbreak in England

A 3rd death has been linked to a Mycobacterium chelonae outbreak at Cambridge’s Royal Papworth Hospital, England. A 26-year-old patient underwent a double lung and heart transplant in June 2019. The...

How a virus packages its genetic material

Simulations by UC Riverside-led team could help design nanocontainers used in drug delivery Each simple RNA virus has a genome, its “native RNA.” This genome dictates how the virus replicates in cells to...

Influenza and the ‘Holy Grail’ vaccine

The influenza virus caused between 9–41 million illnesses and 12–52,000 deaths in the United States each year between 2010 and 2020. In a “bad” flu year, around 30,000 people die in the UK from flu and...

Japanese encephalitis virus situation declared a Communicable Disease Incident of National Significance

Australia’s Acting Chief Medical Officer, Dr Sonya Bennett, has declared the unfolding situation in Australia concerning the Japanese encephalitis virus (JEV) a Communicable Disease Incident of National...

RNA interference as a new approach for the treatment of COVID-19

A research team led by the Technical University of Munich (TUM) has successfully used specific enzymes to destroy the genetic information of SARS-CoV-2 directly after the virus penetrates the cell. The...

Effectiveness of TBE vaccination

Background During the last 30 years, the number of reported TBE cases in Europe has increased by more than 193%, despite two effective TBE vaccines (FSME Immune and Encepur) being available. The raison for...

New study on meningococcal disease

The Latin American Society of Pediatric Infectology (SLIPE for its acronym in Spanish) is working hard to strengthen the vaccination recommendations as the most effective method to prevent meningococcal...

ACIP proposed recommendation for tick-borne encephalitis (TBE) vaccine

The Advisory Committee on Immunization Practices (ACIP) voted on February 23, 2022, to recommend a TBE vaccine for people 12 months of age and older, who are travelling to TBE-endemic areas. TBE is a viral...

New study identifies African “hotspot” for highly infectious diseases

A regional corner of Africa is a hotspot for cases of HIV, tuberculosis and malaria, prompting researchers to call for targeted health support rather than a national response. The new research, published in...

Malawi declares polio outbreak

The Global Polio Laboratory Network (GPLN) has confirmed the presence of a type 1 wild poliovirus (WPV1) in a child suffering from paralysis in Lilongwe, the capital of Malawi. Analysis shows that the virus is...

Climate change and extreme weather will have complex effects on infectious disease transmission

Temperature variation affects pathogens and their hosts in distinct ways, and these organisms are influenced by the type of variation and the average background temperature it is applied to. Temperature...

A promising new vaccine for SARS-CoV-2 and influenza

The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, along with the continuous transmission of influenza viruses and other coronaviruses, remains a serious global threat to public...

Waning of COVID-19 vaccine effectiveness: individual and public health risk

High coverage rates of vaccination against COVID-19 are envisaged to end the pandemic. However, waning of vaccine-induced protection is a growing concern that has been fostered by data on vaccine effectiveness...

Rich countries still need to step up on global COVID vaccine access

Among the G20 goals being pursued by the Indonesian chair this year is ‘ensuring equitable access to COVID-19 vaccines’. This has become a pressing task, though one that’s part of a bigger picture. Developing...

Discovery of protective RNA mechanism informs pursuit to develop anti-viral drugs

In the long-term battle between a herpesvirus and its human host, a University of Massachusetts Amherst virologist and her team of students have identified some human RNA able to resist the viral takeover –...

Cholera epidemic in Cameroon: the resounding need for multi-sectoral national and trans-border collaboration

Introduction As of January 30, 2022, Cameroon has recorded 1,102 cholera cases across five Regions. The outbreak has already claimed the lives of 32 persons. These figures were reported by the Cameroon...

Syphilis is resurging in the United States: once on the brink of eradication, now raging again

The Covid-19 pandemic has understandably dominated the news cycle for almost 2 years now. As we hopefully get past the Omicron variant, it’s important not to lose sight of the currently over 7 million...

Scientists propose cause of symptoms, treatment for long COVID-19

Two studies to be presented at upcoming professional society meetings suggest that some long COVID-19 symptoms may be related to the effect of SARS-CoV-2 on the vagus nerve and that the use of enhanced...

Long-term cardiovascular outcomes of COVID-19

The cardiovascular complications of acute coronavirus disease 2019 (COVID-19) are well described, but the post-acute cardiovascular manifestations of COVID-19 have not yet been comprehensively characterized...

Study shows new drug combination more effective against SARS-CoV-2

Researchers at the University of Maryland School of Medicine (UMSOM) and University of Pennsylvania Perelman School of Medicine have identified a powerful combination of antivirals to treat COVID-19. The...

Afghanistan faces raging measles outbreak

At least 74 children have died following an outbreak of measles in Afghanistan’s northern province of Badakhshan, a provincial official said on 6. Feb 2022. Most of the children who lost their lives were...

Study finds previous COVID-19 infection, but not vaccination, improves performance of antibodies and potentially provides longer-term protection

New research to be presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2022, Lisbon, 23-26 April) shows that, although over time the number of SARS-CoV-2...

Trials start of mRNA vaccine for HIV

First steps towards protection from the many and variable viral strains Volunteers in the US recently received the first experimental doses of a new type of HIV vaccine. Using Moderna’s mRNA platform, the...

Vaccines SputnikV and Sinopharm against COVID-19: comparative research of immunogenicity and reactogenicity

In 2020–2021, a group of researchers from Gomel State Medical University conducted a prospective comparative clinical research that clearly demonstrates the differences in immunogenicity and reactogenicity of...

Burden of TBE, Sweden

Background In Sweden, the number of TBE cases have dramatically increased over the past three decades, with an average of 328 notified cases annually during the past 5 years (2017–2021), which corresponds to...

COVID-19 human challenge study reveals detailed insights into infection

Findings from the UK’s world-leading human challenge study provide new insights into mild infections with SARS-CoV-2 in healthy young adults. The collaborative study is the first in the world to perform...

Cameroon’s NITAG recommends COVID-19 vaccination among pregnant and lactating women

Like in many countries, Cameroon, a Central African Country, was quick to introduce and roll out COVID-19 vaccines. These introductions were preceded by a recommendation for the National Immunization Technical...

Braving the odds to provide immunization services in a fishing community, Cameroon

Immunization is a success story for global health and development. It is an intervention that has saved millions of lives every year. Each year, over 116 million infants – 86% of all infants born in that year...

Previous infection provides protection against COVID-19 for several months

People previously infected with SARS-CoV-2 are substantially protected against COVID-19 for several months, even in the absence of vaccination, a study found. Beyond that, however, their natural immunity wanes...

Norwegian Institute of Public Health (NIPH) warns of an ongoing outbreak of Pseudomonas aeruginosa

A Pseudomonas aeruginosa outbreak in Northern Norway was discovered in November 2021. Three patients, admitted for COVID-19, fell seriously ill and died of blood stream infection with identical Pseudomonas...

Cholera Outbreak in the South of the Philippines

A Cholera outbreak was detected in Barangay Santiago, Caraga Davao Oriental, the Philippines, on January 31, 2022, affecting 265 residents. The area’s existing water system, in need of rehabilitation, is...

Leptospirosis in The Philippines

In mid-2021, The Philippines Department of Health announced a 13% increase of Leptospirosis cases compared to the same period in 2020 with a case fatality rate of 11.4%. Global estimates are around 500,000...

Intranasal flu vaccine with nanoparticles offers robust protection, researchers find

An influenza vaccine administered through the nose and constructed with nanoparticles that enhance immune response offers strong protection against different influenza virus strains, according to researchers...

Mix-and-match of COVID-19 vaccine boosters found to be safe and effective

In adults who had previously received a full regimen of a COVID-19 vaccine approved or authorized by the Food and Drug Administration (FDA), an additional dose of any of these COVID-19 vaccines was safe and...

Zika vaccine shows promising results in preclinical studies

A Zika virus vaccine candidate is effective at preventing the Zika virus passing from mother to fetus in preclinical animal studies, according to a new study in the journal npj Vaccines. The research is a...

Typhoid fever in the Philippines

In January 2022, a cluster of around 30 people were hospitalized due to typhoid fever in Manaulanan village, North Cotabato, The Philippines. The village does not have access to potable water. In response to...

Rabies in Iloilo, The Philippines

Despite the goal of becoming rabies free by 2022, 12 deaths due to rabies were reported in 2021 in the province of Iloilo, The Philippines, a 3-fold increase from 2020. Five of the 6 towns/cities from where...