Global Health Press

Viral role in Alzheimer’s Disease discovered

Researchers from Oxford’s Institute of Population Ageing, Tufts University and the University of Manchester have discovered that common viruses appear to play a role in some cases of Alzheimer’s disease (AD)...

Global Health Cast Edition 9

Ninth Edition of the Global Health Cast presented by Prof. Schmitt, Dr. Sanicas and Dr. Rapi Nteene. 00:00 Introduction 00:58 What we talk about today 01:14 COVID-19 update 02:56 Monkeypox update 04:28 Adverse...

Tuberculosis vaccine passes safety test

The vaccine candidate VPM1002 shows its safety in a study with HIV- and non-HIV-exposed newborns No other infectious disease has killed more people than tuberculosis. Currently, only one vaccine is available...

Giant viruses build a cell nucleus surprisingly like our own

New technologies provide unprecedented view of virus’ ‘weird biology’—critical for future biomedical applications against bacterial infections Humans aren’t the only targets for viruses. Like us, bacteria...

New monkeypox tracing method can analyze multiple samples and quickly detect virus strains

Dutch company Molecular Biology Systems (MBS), in collaboration with Amsterdam University Medical Center, and researchers from the Danish Rigshospitalet, has developed a fast typing method to trace monkeypox...

Global Health Cast Edition 8

Eighth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. Topics Covered: 00:00 Introduction 00:44 COVID19 Update 02:09 COVID19 Q&A 20:17 Main Messages Today 21:58 Cartoon of the...

Common viruses may be triggering the onset of Alzheimer’s disease

Alzheimer’s disease can begin almost imperceptibly, often masquerading in the early months or years as forgetfulness that is common in older age. What causes the disease remains largely a mystery. But...

Chinese scientists propose a new live-virus flu vaccine

Using attenuated, live viruses as vaccines is a promising strategy to reduce the impact of viral infectious diseases, such as influenza. Traditional live-attenuated virus vaccines have, however, often been...

Promising developments in pursuit to design pan-coronavirus vaccine

Researchers at the Francis Crick Institute have shown that a specific area of the SARS-CoV-2 spike protein is a promising target for a pan-coronavirus vaccine that could offer some protection against new virus...

Dreaming up new proteins, AI churns out possible medicines and vaccines

Computational biologist Jue Wang was already striving to develop an artificial intelligence (AI) to churn out candidate medicines when he had to rush his 2-year-old son to the hospital with a potentially...

Global Health Cast Edition 7

Seventh Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. Topics Covered: 00:00 Introduction 00:32 What we talk about today 00:49 COVID-19 update 05:58 Good Medical Language (GML)...

How vaccine-related fears affect the flu shot experience

A novel long-term study of how vaccine-related fears influence flu shot outcomes has found that these fears not only reduce vaccination, but also fuel symptoms of dizziness and lightheadedness at the time of...

A novel COVID-19 vaccine using modified bacterial DNA

Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, describe a different way to build a COVID-19 vaccine, one that would, in theory, remain effective against new...

New York detects vaccine-derived polio case

Health officials in New York  announced a vaccine-derived poliovirus type 2 case, which involves a person in Rockland County, prompting a vaccination push for the unimmunized and those who aren’t fully...

Ghana declares first-ever outbreak of Marburg virus disease

Ghana has announced the country’s first outbreak of Marburg virus disease. The Institute Pasteur in Dakar, Senegal, received samples from two patients from the southern Ashanti region of Ghana – both deceased...

Booster shots offset some Omicron immune evasion tactics

Although Omicron subvariants of the SARS-CoV-2 pandemic coronavirus have evolved to evade antibody responses from the primary COVID-19 vaccine series, a new laboratory study suggests current vaccine boosters...

Vaccine-induced immune response to omicron wanes substantially over time

Although COVID-19 booster vaccinations in adults elicit high levels of neutralizing antibodies against the Omicron variant of SARS-CoV-2, antibody levels decrease substantially within 3 months, according to...

Global Health Cast Edition 6

Sixth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. Topics Covered: 00:00 Introduction 0:29 What we talk about today 01:00 COVID-19 update 05:10 Do epidemics increase with...

Global Institute simplifies vaccine manufacturing for developing world

The concentration of biomanufacturing expertise in industrial nations left low- and middle-income countries with few ways to obtain the COVID-19 vaccines when they became available. That limited availability...

Vaccine-derived poliovirus Type 2 in London’s environmental samples

The UK Heath Security Agency (UKHSA) has found poliovirus in sewage samples collected from the London Beckton Sewage Treatment Works. As part of routine surveillance, these detections occurred when an...

Global Health Cast Edition 5

Fifth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. Topics Covered: 00:00 Introduction 00:42 COVID-19 update and news 10:25 Can bio-scans measure body oscillations predicting...

Study shows increase in COVID-19 vaccine acceptance around the world

COVID-19 vaccine acceptance increased 3.7% between 2020 and 2021, according to a new study from researchers at the CUNY Graduate School of Public Health and Health Policy (CUNY SPH), the Barcelona Institute...

Familiarity breeds exempt: why staph vaccines don’t work in humans

The sometimes-pathogenic bacteria has a long and intimate relationship with people, one that helps it fend off our immune response For the most part, the bacterium Staphylococcus aureus is common and harmless...

Global Health Cast Special 1: Monkeypox

First Special of the Global Health Cast presented by Prof. Schmitt and Dr. Florian Lienert. Download PDFs: Video Presentation / VacciTUTOR Chapter 58 – Smallpox and Monkeypox. Click here for more Global...

Mutations in virus causing monkeypox outbreak allow it to spread more easily

The strain of the virus in the current monkeypox outbreak in nonendemic countries likely diverged from the monkeypox virus that caused a 2018-19 Nigerian outbreak and has far more mutations than would be...

Scientists discover key to hepatitis A virus replication, show drug effectiveness

With no current treatments for hepatitis A, UNC School of Medicine scientists led by Stanley M. Lemon, MD, discovered how a protein and enzymes interact to allow hepatitis A virus to replicate, and they used a...

Global Health Cast Edition 4

Fourth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. Topics Covered: 00:00 Introduction 00:35 Ticks don’t bite . . . as they do not have teeth 02:29 COVID-19 update and...

Some viruses make you smell tastier to mosquitoes

Zika and dengue fever viruses alter the scent of mice and humans they infect, researchers report in the June 30 issue of Cell. The altered scent attracts mosquitoes, which bite the host, drink their infected...

NIH scientists discover norovirus and other “stomach viruses” can spread through saliva

A class of viruses known to cause severe diarrheal diseases – including the one famous for widespread outbreaks on cruise ships – can grow in the salivary glands of mice and spread through their saliva...

How can a human challenge study help tackle the global impact of Salmonella?

Dr Malick Gibani explains how a human challenge study for non-typhoidal Salmonella can support vaccine development and protect vulnerable populations. Salmonella infection (salmonellosis) is a common disease...

Discovery of new Covid infection mechanism offers clue to SARS-CoV-2 leap to humans

One of the best-known aspects of the Covid-19 pandemic is that the virus ‘jumped’ into people from animals – perhaps bats or pangolins – in a process known as zoonotic transfer. What hasn’t been clear to...

Global Health Cast Edition 3

Third Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. Topics Covered: 00:00 Introduction 01:00 COVID-19 update and news 05:08 Can scientists/physicians make a difference in...

Down-regulating TAO2 prevents influenza from replicating in cells and could provide new target for antiviral therapies

A collaborative study from UT Southwestern scientists has identified a new function for a protein called TAO2 that appears to be key to inhibiting replication of the influenza virus, which sickens millions of...

Women more likely to have long COVID, different symptom profile

Women are significantly more likely than men to experience long COVID, with symptoms that follow a distinct clinical pattern, researchers reported. They said more efforts are needed to explore sex differences...

Understanding poor vaccine responses in individuals with weakened immune systems

When the COVID-19 vaccine first became available, people eagerly signed up for coveted slots to boost their antibodies against the virus that shut down much of the world. But not everyone who rolled up their...

Emory participating in trial to test mRNA HIV vaccine in humans

Emory University is participating in a Phase I clinical trial to evaluate the use of messenger RNA (mRNA) technology in HIV vaccines for the first time in humans. The trial, IAVI G002, was launched earlier...

Global Health Cast Edition 2

Topics Covered: 00:00 – Introduction 00:55 – Global COVID-19 situation: cases continue to decline 05:26 – AZD7442 – mAB for prevention of COVID-19 09:12 – Lack of Immune response to...

Going all the way: Scientists prove inhaled vaccines offer better protection than nasal sprays

Inhaled aerosol vaccines provide far better protection and stronger immunity than nasal sprays, McMaster scientists who compared respiratory vaccine-delivery systems have confirmed. While nasal sprays reach...

Monkeypox DNA hints virus has been spreading in people for years

Genome sequencing confirms that monkeypox cases outside Africa are all related and suggests the virus responsible may have been circulating in people since 2017 Rather than jumping to humans from animals...

Respiratory virus ‘kills 100,000 children under five’

Respiratory syncytial virus (RSV) is common cause of infections such as pneumonia. Most cases and deaths in young children occur in lower-income countries. Passive immunisation campaign urged for babies under...

As monkeypox threat grows, scientists debate best vaccine strategy

Favored shot is a seemingly safer smallpox vaccine, but efficacy remains unclear In 1959, German microbiologist Anton Mayr took a strain of vaccinia, a poxvirus used to inoculate against smallpox, and started...

Global Health Cast Edition 1

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Legionellosis Outbreak in New York City

The number of Legionnaires’ disease cases has increased from 19 to 24, and the death toll has risen from 1 to 2, the New York City health department said on June 1st, 2022. Four people are currently...

No more flu for you? Discovery blocks influenza virus’ replication in cells

SUMOylation inhibitor could lead to highly effective ways to treat the flu and other respiratory viruses It happens every year, especially in winter. A virus saunters into your wide-open respiratory tract...

Real-time, accurate virus detection method could help fight next pandemic

A method of highly accurate and sensitive virus identification using Raman spectroscopy, a portable virus capture device and machine learning could enable real-time virus detection and identification to help...

International study reveals factors contributing to COVID-19 vaccine hesitancy among healthcare providers

A new 23-country study by a multidisciplinary team of researchers in the journal Vaccine, published by Elsevier, sheds light on the factors that contribute to COVID-19 vaccine hesitancy among healthcare...

New type of pneumococcal vaccine developed by KI scientists

Researchers at Karolinska Institutet have identified a new vaccine candidate against pneumococci, bacteria that can cause pneumonia, sepsis, and meningitis. The vaccine molecules comprise nano-sized membrane...

How COVID-19 created dramatic changes in a ‘winter virus’

The pandemic is changing the genetic landscape of virus strains A University of Sydney- led study reveals how the pandemic has changed the normal patterns of winter viruses in Australia, with new strains...

Viruses that were on hiatus during Covid are back — and behaving in unexpected ways

For nearly two years, as the Covid pandemic disrupted life around the globe, other infectious diseases were in retreat. Now, as the world rapidly dismantles the measures put in place to slow spread of Covid...

China’s hope for homegrown mRNA vaccine holds back nation

China has not been using the kind of COVID-19 vaccine that has proven to offer the best protection against the virus. The country is working through its biggest coronavirus outbreak yet without a tool it could...

Are we doing enough to prevent future pandemics?

Damage to our climate, shifting patterns of animal and human interaction, urbanization, the creep of antimicrobial resistance (AMR) and increased international trade and travel are all creating more...

Confirmed monkeypox case in North America

Scientists at the Centers for Disease Control and Prevention (CDC) are collaborating with the Massachusetts Department of Public Health to investigate a case of monkeypox in a Massachusetts resident who had...

Smallpox vaccine, IMVANEX, to be supplied to unknown European country in response to monkeypox

Bavarian Nordic A/S announced Thursday that the Company has secured a contract with an undisclosed European country to supply its IMVANEX® smallpox vaccine in response to new cases of monkeypox evolving during...

mRNA HIV vaccine candidate launches first-in-Africa study

The nonprofit scientific research organization IAVI and Massachusetts-based Moderna, Inc. recently announced that a Phase I clinical trial of an mRNA HIV vaccine antigen (mRNA-1644) will soon launch at the...

Smallpox vaccines can be 85% effective against monkeypox: WHO

Data shows that vaccines that were used to eradicate smallpox are up to 85 percent effective against monkeypox, according to the World Health Organization (WHO). There isn’t a specific vaccine for...

The World Vaccine Day – GHP-Symposium

 Keynote Speakers Time Topic Presenter 1:00pm Opening: GHP website Prof. Dr. Heinz Josef-Schmitt Mainz, Germany 1:05pm COVID Summary (45 mins) Prof. Robert Booy Sydney, Australia 1:50pm Measles Elimination...

Why is the 100-year-old BCG vaccine so broadly protective in newborns?

The century-old Bacille Calmette-Guérin (BCG) vaccine against tuberculosis is one of the world’s oldest and most widely used vaccines, used to immunize 100 million newborns every year. Given in countries with...

Climate change will force new animal encounters — and boost viral outbreaks

Over the next 50 years, climate change could drive over 15,000 new cases of mammals transmitting viruses to other mammals, according to a study published in Nature. It’s one of the first to predict how global...

Vaccine-preventable disease outbreaks on the rise in Africa

Brazzaville – Africa is witnessing a surge in outbreaks of vaccine-preventable diseases over the past year. Almost 17,500 cases of measles were recorded in the African region between January and March 2022...

Omicron less severe than Delta but more easily evades boosters

Three new observational studies from Scotland, Denmark, and the United States detail reduced hospitalizations and emergency department (ED) visits for Omicron COVID-19 infections relative to those caused by...

Multi-Country – Acute, severe hepatitis of unknown origin in children

Outbreak at a glance: Since the WHO Disease Outbreak News on Acute hepatitis of unknown etiology – the United Kingdom of Great Britain and Northern Ireland was published on 15 April 2022, there have been...

Population-wide study of COVID-19 vaccination shows that mix-and-match approach to booster vaccination offers the best protection

A new study on Chile’s national COVID-19 vaccination program, to be presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2022, Lisbon 23-26), and published in...

New Ebola outbreak declared in the Democratic Republic of Congo

The health authorities of the African nation declared a new outbreak of Ebola after a case was confirmed in Mbandaka, a city in the north-western Equateur Province, the World Health Organization (WHO) reported...

Effect of 13-valent pneumococcal conjugate vaccine on hospitalization in older adults

Invasive pneumococcal disease rates have decreased substantially in children and adults since 2010, when use of 13-valent pneumococcal conjugate vaccine in children became the standard of care. Adults 65 years...

Smartwatches and fitness bands reveal individual physiological responses to COVID-19 vaccine

A new digital health study by researchers at Scripps Research shows how data from wearable sensors, such as smartwatches and fitness bands, can track a person’s physiological response to the COVID-19...

Ebola virus hides out in brain

Monkeys treated with monoclonal antibodies fully recovered, but infection recurred The Ebola virus can hide in the brains of monkeys that have recovered after medical treatment without causing symptoms and...

Experts warn of possible XE subvariant outbreak in Japan

Public health experts have warned of a possible outbreak of the XE subvariant of the omicron coronavirus variant in Japan, where signs of a potential seventh COVID-19 wave are emerging. The health ministry...

Europe on alert as UK investigates mysterious cases of severe hepatitis in young children

The World Health Organization (WHO) and the EU’s health agency have issued warnings to other countries to be on the alert following a mysterious spike in cases of severe liver disease in children in the UK...

Why US-Universities Battle Meningitis Outbreaks

The CDC issued a health warning on April 9, 2022 about an outbreak of meningococcal disease in Florida. Multiple meningococcal disease cases in college students had been reported in the state of Florida over...

New findings show effectiveness of meningococcal B vaccine against gonorrhoea

Researchers at The University of Adelaide have found that the meningococcal B vaccine could improve protection against gonorrhoea in addition to protection against meningococcal B meningitis. This significant...

Case of probable transmission of tick-borne encephalitis virus from an unvaccinated mother to an infant through breast-feeding

A recent study published in Emerging Infectious Diseases discusses a case report of the probable vertical transmission of tick-borne encephalitis virus (TBEV) from an unvaccinated mother to her newborn via...

New study from UCI reveals how to rejuvenate the immune system of elderly people and reduce their risk of infectious disease

A new study, led by researchers from the University of California, Irvine, identifies a reason for why older adults are significantly more susceptible to infectious diseases than younger people, a critical...

One-dose Human Papillomavirus (HPV) vaccine offers solid protection against cervical cancer

The 4-7 April convening of the WHO Strategic Advisory Group of Experts on Immunization (SAGE) evaluated the evidence that has been emerging over past years that single-dose schedules provide comparable...

Deciphering insect-borne viruses

There is no treatment or vaccine for the West Nile, dengue, or Zika viruses. These infections caused by flaviviruses—mosquito-borne viruses—are a major public health concern worldwide. Understanding their...

IU awarded $1.2M to develop first-of-its-kind rotavirus-norovirus vaccine for infants

Indiana University will further develop a new technology for a combination oral rotavirus-norovirus vaccine for infants, thanks to a $1.2 million grant from venture capital firm GIVAX Inc. The technology...

ECDC and EMA issue advice on fourth doses of mRNA COVID-19 vaccines

The European Centre for Disease Prevention and Control (ECDC) and EMA’s COVID-19 task force (ETF) have concluded that it is too early to consider using a fourth dose of mRNA COVID-19 vaccines (Pfizer’s...

Vaccelerate: EU-Commission funded academic consortium to speed up vaccine development

The COVID pandemic showed lack of preparedness in many public health areas all over Europe. One such gap – often overlooked – is the lack of tools to rapidly conduct clinical studies on new vaccines...

A spotlight on avian influenza

Behind geopolitical conflicts and the ongoing COVID-19 pandemic are the sporadic chains of avian influenza outbreaks with 79 notifications spread across countries from Africa, Asia, Europe and America within...

Pfizer, Moderna vaccines aren’t the same; study finds antibody differences

The mRNA-based COVID-19 vaccines made by Pfizer/BioNTech and Moderna have proven highly effective at priming our immune systems to fight the pandemic coronavirus—preventing substantial amounts of infection...

TBE virus infection without central nervous system involvement

Background Most TBE virus infections remain asymptomatic; but when the infection is symptomatic, the disease can manifest with fever and can often involve the central nervous system (CNS) which leads to tick...

Japan disease institute says that aerosol transmission could lead to COVID infection

Japan’s National Institute of Infectious Diseases (NIID) announced on its website on March 28 that the coronavirus can be transmitted through inhalation of aerosols floating in the air containing the...

Noma, a neglected tropical disease?

Noma is also known as necrotizing ulcerative stomatitis or cancrum oris, a severely debilitating orofacial infection. It has been known for centuries and was already reported by Hippocrates and other...

Test can predict severe dengue infection, study finds

Researchers have created a test that can predict which dengue patients will likely have mild symptoms and which should be clinically monitored for a high risk of severe illness. Most of the about 390 million...

NUS-Monash University collaboration produces universal flu vaccine candidate

Influenza, commonly referred to as “flu”, is a major global public health concern and a huge economic burden to societies. Seasonal influenza epidemics afflict between 13 to 100 million individuals annually...

Vaccine-induced T cells provide long-lasting immune response to COVID-19: study

The human body’s T cells provide long-lasting memory against the virus following vaccination or infection from COVID-19, a study led by the Peter Doherty Institute for Infection and Immunity (Doherty...

How dangerous is BA.2, the new COVID-19 variant?

As COVID-19 case numbers climb in East Asia and now Europe — a surge largely attributed to the BA.2 subvariant of omicron — it makes sense that concern would rise in the U.S. It’s happened before during the...

Pertussis outbreak in indigenous population in Colombia

A Bordetella pertussis outbreak has been reported by the National Institute of Health (INS) of Colombia in the Kogui community, an indigenous group living in the Sierra Nevada de Santa Marta mountains in...

Nanoparticle-based COVID-19 vaccine could target future infectious diseases

Just one dose of a new nanoparticle-based COVID-19 vaccine was enough to produce an immune response in animals on track with vaccines currently in clinical use. And with minor changes, Northwestern University...

Effectiveness of antibiotics significantly reduced when multiple bugs present

A study has found that much higher doses of antibiotics are needed to eliminate a bacterial infection of the airways when other microbes are present. It helps explain why respiratory infections often persist...

Kenya takes a strong stand in Covid-19 vaccinations to minimize the spread of the disease

Kenya identified its first case of Covid-19 on 12th March 2020. It has since then undertaken a series of measures to contain the spread and management of the disease in the country. In a population of...

New modelling framework developed to improve infectious disease control

A new model to analyse infectious disease outbreak data has been developed by mathematicians that could be used to improve disease tracking and control. Researchers from the University of Nottingham developed...

New study confirms bioengineered RSV protein vaccine evokes protective immune response

Close interactions with infectious disease set both UC Santa Cruz graduate student Ana Nuñez Castrejon and Associate Professor of Biomolecular Engineering Rebecca DuBois on the path of studying respiratory...

Nosocomial Mycobacterioides chelonae Outbreak in England

A 3rd death has been linked to a Mycobacterium chelonae outbreak at Cambridge’s Royal Papworth Hospital, England. A 26-year-old patient underwent a double lung and heart transplant in June 2019. The...

How a virus packages its genetic material

Simulations by UC Riverside-led team could help design nanocontainers used in drug delivery Each simple RNA virus has a genome, its “native RNA.” This genome dictates how the virus replicates in cells to...

Influenza and the ‘Holy Grail’ vaccine

The influenza virus caused between 9–41 million illnesses and 12–52,000 deaths in the United States each year between 2010 and 2020. In a “bad” flu year, around 30,000 people die in the UK from flu and...

Japanese encephalitis virus situation declared a Communicable Disease Incident of National Significance

Australia’s Acting Chief Medical Officer, Dr Sonya Bennett, has declared the unfolding situation in Australia concerning the Japanese encephalitis virus (JEV) a Communicable Disease Incident of National...

RNA interference as a new approach for the treatment of COVID-19

A research team led by the Technical University of Munich (TUM) has successfully used specific enzymes to destroy the genetic information of SARS-CoV-2 directly after the virus penetrates the cell. The...

Effectiveness of TBE vaccination

Background During the last 30 years, the number of reported TBE cases in Europe has increased by more than 193%, despite two effective TBE vaccines (FSME Immune and Encepur) being available. The raison for...

New study on meningococcal disease

The Latin American Society of Pediatric Infectology (SLIPE for its acronym in Spanish) is working hard to strengthen the vaccination recommendations as the most effective method to prevent meningococcal...