Global Health Press

New vaccine needed for serious childhood pneumonia

A UNSW Sydney-led medical research team has called for a new vaccine, improved strategies and enhanced monitoring to combat serious complications from childhood pneumonia. The researchers examined the impact...

Researchers identify five plasma proteins related to severe COVID-19

Just as oil is essential to keep a car’s motor running, blood is essential to keep the body functioning. The presence of particular proteins in the plasma, the liquid component of blood, may signal the...

Global Health Cast Edition 21

Twenty-first Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. 00:00 Introduction 00:54 COVID-19 update 03:49 TBE-ISW meeting in Vienna (end November 2022) 06:01 NEW US CDC data on...

Researchers test mRNA technology for universal flu vaccine

An experimental vaccine provided broad protection against all 20 known influenza A and B virus subtypes in initial tests in mice and ferrets, potentially opening a pathway to a universal flu shot that might...

Scientists reveal key differences in immune response to inactivated virus and mRNA COVID-19 vaccines

Although the total magnitude of the T-cell responses induced by mRNA and inactivated SARS-CoV-2 vaccines are comparable, the similarity ends there. This is according to a new study led by scientists from Duke...

Unusual Zika virus-specific antibody exhibits ultrapotent neutralization

An unusual type of antibody that even at miniscule levels neutralizes the Zika virus and renders the virus infection undetectable in preclinical models has been identified by a team led by Weill Cornell...

Competition between respiratory viruses may hold off a ‘tripledemic’ this winter

Triple threat. Tripledemic. A viral perfect storm. These frightening phrases have dominated recent headlines as some health officials, clinicians, and scientists forecast that SARS-CoV-2, influenza, and...

Stanford team re-engineers virus to deliver therapies to cells

Stanford researchers have ripped the guts out of a virus and totally redesigned its core to repurpose its infectious capabilities into a safe vehicle for delivering vaccines and therapies directly where they...

Global Health Cast Edition 20

Twentieth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. 00:00 Introduction 00:28 Human population to grow to 8 billion for the first time today 03:00 COVID-19 update 04:57 Death...

Investigating COVID-19 deaths for children and young people

A new study conducted in England shows that the risk of death due to COVID-19 remains very low for children and young people, and most deaths occur in those with underlying health conditions. Marta Bertran of...

Global Health Cast Edition 19

Nineteenth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. 00:00 Introduction 01:22 COVID-19 update 03:24 COVID 19 “variant soup” 05:50 COVID-19 likely spread through floors...

Breast cancer vaccine safely generates anti-tumor immunity

Study findings suggest that a vaccine could be used to prevent or treat a particularly aggressive form of breast cancer. An experimental vaccine against breast cancer safely generated a strong immune response...

OPV protects against infectious disease mortality

Oral polio vaccine given at birth to children in resource-limited countries is safe and also may be protective against other deadly infectious diseases, according to a recent study. “Routine vaccines may have...

Effects of MVA85A vaccine on tuberculosis

A new systematic review of animal studies testing a vaccine for tuberculosis raises questions about whether the studies provided sufficient evidence to move into trials of children. The new vaccine was a virus...

China-based researchers develop rapid testing methods for monkeypox virus

Some China-based researchers have recently developed three rapid testing methods for monkeypox virus (MPXV) that can provide the result in 20 to 30 minutes and are significantly faster than the traditional...

Global Health Cast Edition 18

Eighteenth Edition of the Global Health Cast presented by Prof. Schmitt, Dr. Sanicas and Dr. Florian Lienert. 00:00 Introduction 00:53 COVID-19 update 06:07 Update on SARS-CoV-2 variants / subvariants 14:01...

ACIP revises pneumococcal vaccine recommendations for aged patients

The Advisory Committee on Immunization Practices has updated its vaccination recommendations for immunocompetent adults aged 65 years or older to extend the interval between receipt of the Prevnar 13 and...

Marburg Virus: A highly contagious and deadly virus

Emerging infectious diseases are affecting public health and economies globally. Still living in the COVID-19 pandemic and now seeing another global public health emergency with monkeypox, the world must also...

Viral infections are less frequent but more severe in people with Down syndrome due to oscillating immune response

Individuals with Down syndrome have less-frequent viral infections, but when present, these infections lead to more severe disease. New findings publishing on October 14 in the journal Immunity show that this...

Vaccine with virus-like nanoparticles found to be effective treatment for respiratory syncytial virus (RSV)

Researchers at Georgia State University say their findings, published July 14 in the International Journal of Nanomedicine, suggest their nano-engineered vaccine induces long-term protection against...

Global Health Cast Edition 17

Seventeenth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. 00:00 Introduction 00:45 COVID19 epidemiology-update 02:03 COVID19 vaccination update 05:20 MPX update 06:42 COVID19:...

Independent Task Force on COVID-19 and other Pandemics: origins, prevention, and response

The Independent Task Force on COVID-19 and other Pandemics announced that their report “Pandemic Origins and a One Health Approach to Preparedness and Prevention: Solutions Based on SARS-CoV-2 and Other RNA...

Global Health Cast Edition 16

Sixteenth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. 00:00 Introduction 01:14 COVID19 update 03:33 Excess deaths from COVID19 in US-Republican vs. Democrats 05:50 Primary...

Other SARS-CoV-2 proteins are important for disease severity, aside from the spike

University of Maryland School of Medicine researchers have identified how multiple genes of SARS-CoV-2 affect disease severity, which could lead to new ways in how we develop future vaccines or develop newer...

Misinformation about vaccine safety drives reluctance to vaccinate children

As of late September 2022, nearly 78% of U.S. adults but only 31% of children ages 5 to 11 had completed their primary series of vaccinations against COVID-19, according to health authorities. In an open...

Global Health Cast SPECIAL 5: Healthcare in Mozambique

Fifth SPECIAL Edition on Healthcare in Mozambique of the Global Health Cast presented by Prof. Schmitt and Dr. Delphine Goux.
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Global Health Cast Edition 15

Fifteenth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. 00:00 Introduction 00:37 COVID19 Update 04:24 MPX Update 13:26 More on COVID19 25:02 Cartoon of the day Download...

First-in-human clinical trial confirms novel HIV vaccine approach developed by IAVI and Scripps Research

A phase 1 clinical trial testing a novel vaccine approach to prevent HIV has produced promising results, IAVI and Scripps Research announced. The vaccine showed success in stimulating production of rare immune...

Global Health Cast Edition 14

Fourteenth Edition of the Global Health Cast presented by Prof. Schmitt. 00:00 Intro 01:12 Current vaccines and vaccine development 08:41 Coming soon (recently licensed & phase 3) 54:34 Think about the...

Lassa virus endemic area may expand dramatically in coming decades

New analysis by scientists at Scripps Research and University of Brussels finds that climate change and other factors could soon make deadly Lassa fever a much bigger public health problem in Africa In the...

Traditional incentives don’t offset COVID vaccine hesitancy

Neither money nor other nudges are enough to persuade vaccine-hesitant people to get the COVID-19 vaccine, a new USC study shows. The findings, published recently in the journal Vaccine, suggest the standard...

Global Health Cast SPECIAL 3: CLCI; CVS Cameroon

Third SPECIAL Edition on CLCI; CVS Cameroon of the Global Health Cast presented by Prof. Schmitt, Dr. Holt and Dr. Saidu.
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Newly discovered COVID‑like virus could infect humans, resist vaccines

A recently discovered virus in a Russian bat that is similar to SARS-CoV-2, the virus behind COVID-19, is likely capable of infecting humans and, if it were to spillover, is resistant to current vaccines. A...

Gut microbiota in early life may affect vaccine efficacy

Bifidobacterium and Bacteroides in the gut microbiome are important to vaccine responsiveness and could be used in vaccine adjuvants in the future, a recent review shows. Gut microbiota in early life can...

Uganda declares Ebola Virus Disease outbreak

The health authorities in Uganda declared an outbreak of Ebola after a case of the Sudan ebolavirus was confirmed in Mubende district in the central part of the country. The Uganda Virus Research Institute...

Global Health Cast SPECIAL 4: CEPI

Forth SPECIAL Edition on CEPI of the Global Health Cast presented by Prof. Schmitt, Stig Tollefsen and Dr. Sanicas.
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Individual COVID-19 infections include multiple variants of the SARS-CoV-2 virus, research shows

Researchers at Case Western Reserve University found wide genetic variation in SARS-CoV-2 viruses among 360 patients whose viral infections were genetically sequenced, showing that all individual infections...

Global Health Cast Edition 13

Thirteenth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. 00:00 Introduction 00:53 COVID19 update 02:34 Monkeypox update 03:38 Long-term cardiac pathology after mild COVID 06:55...

New malaria vaccine with 75% efficacy a potential game-changer

A new R21/Matrix-M malaria vaccine shows 75% efficacy in a Phase2b trial – a potentially game-changing result compared to the WHO-approved RTS,S/AS01 (RTS,S) vaccine. The WHO has said it will continue with the...

Researchers capture live footage of a virus infecting a cell

In a first, scientists have captured on video all the steps a virus follows as it enters and infects a living cell in real time and in three dimensions. They achieved the feat by using advanced imaging called...

Global Health Cast Edition 12

Twelfth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. 00:00 Introduction 00:52 COVID-19 update 03:06 Monkeypox update 04:51 The “antigenic sin” 07:13 Why vaccines may fail 10:23...

SARS-CoV-2 antigen levels linked to patient outcomes

The amount of SARS-CoV-2 antigen measured in the blood of patients hospitalized with COVID-19 is associated with illness severity and other clinical outcomes, according to a new study published in the Annals...

Study raises concerns about the effectiveness of the monkeypox vaccine

An new study is raising concerns about the effectiveness of the monkeypox vaccine being used in the United States and other parts of the world. The work, which has not yet been peer-reviewed, found that two...

mRNA COVID vaccines protect against severe Omicron for at least half a year

COVID-19 mRNA booster vaccines offered protection against severe COVID-19 caused by the Omicron variant for at least 6 months, and three doses of China’s inactivated vaccines were more protective than...

Global Health Cast Edition 11

Eleventh Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. 00:00 Introduction 00:50 COVID-19 update 02:02 Monkeypox update 03:24 Duration of COVID19-induced loss of smell and taste...

Global Health Cast SPECIAL 2: Vaccelerate Volunteer Registry

Second SPECIAL Edition on Vaccelerate Volunteer Registry of the Global Health Cast presented by Prof. Schmitt, Dr. Zoe Pana, Janina Leckler and Prof. Cornely. Download PDF: Video Presentation Click here for...

Travel alert for Chikungunya Virus

Chikungunya virus is endemic in the Indonesian archipelago, and sporadic cases are reported from various islands, including Bali. Bali is a favorite tourist destination, and visitors should be aware of the...

Universal flu vaccine protects against variants of both influenza A and B viruses, biomedical sciences researchers find

A new universal flu vaccine protects against diverse variants of both influenza A and B viruses in mice, according to a new study by researchers in the Institute for Biomedical Sciences at Georgia State...

Tomato flu outbreak in India

Just as we are dealing with the probable emergence of fourth wave of COVID-19, a new virus known as tomato flu, or tomato fever, has emerged in India in the state of Kerala in children younger than 5 years.1...

Over half of infectious diseases made worse by climate change

The link between global warming and the increased risk of diseases spread by organisms such as viruses and bacteria has been well known for a few years – cholera, malaria, Lyme disease, West Nile virus and the...

Genomic studies could impact pneumococcal disease vaccine design

A revolutionary genomic surveillance study has provided the clearest picture yet of the arms race between Streptococcus pneumoniae, the bacterium responsible for a range of illnesses such as pneumococcal...

Will vaccine skeptics change their minds?

A new kind of predictive network model could help determine which people will change their minds about contentious scientific issues when presented with evidence-based information. A new study in Science...

Global Health Cast Edition 10

Tenth Edition of the Global Health Cast presented by Prof. Schmitt, Dr. Sanicas and Dr. Florian Lienert. 00:00 Introduction 01:03 Global COVID-19 situation: cases continue to decline 02:41 Ineffective COVID19...

Scientists develop effective intranasal mumps-based COVID-19 vaccine candidate

New research by the Ohio State University, US, has advanced COVID-19 vaccine work in several ways: using a modified live attenuated mumps virus for delivery, showing that a more stable coronavirus spike...

Henipavirus Outbreak in China

Published in the New England Journal of Medicine, a newly identified Henipavirus, named Langya (LayV), infected farmers and other residents, who believe it may have spread directly or indirectly from shrews –...

Global Health Cast SPECIAL 1: Congratulations Melvin Sanicas

First SPECIAL Edition of the Global Health Cast presented by Prof. Schmitt.
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Study connects climate hazards to 58% of infectious diseases

Climate hazards such as flooding, heat waves and drought have worsened more than half of the hundreds of known infectious diseases in people, including malaria, hantavirus, cholera and anthrax, a study says...

Viral role in Alzheimer’s Disease discovered

Researchers from Oxford’s Institute of Population Ageing, Tufts University and the University of Manchester have discovered that common viruses appear to play a role in some cases of Alzheimer’s disease (AD)...

Global Health Cast Edition 9

Ninth Edition of the Global Health Cast presented by Prof. Schmitt, Dr. Sanicas and Dr. Rapi Nteene. 00:00 Introduction 00:58 What we talk about today 01:14 COVID-19 update 02:56 Monkeypox update 04:28 Adverse...

Tuberculosis vaccine passes safety test

The vaccine candidate VPM1002 shows its safety in a study with HIV- and non-HIV-exposed newborns No other infectious disease has killed more people than tuberculosis. Currently, only one vaccine is available...

Giant viruses build a cell nucleus surprisingly like our own

New technologies provide unprecedented view of virus’ ‘weird biology’—critical for future biomedical applications against bacterial infections Humans aren’t the only targets for viruses. Like us, bacteria...

New monkeypox tracing method can analyze multiple samples and quickly detect virus strains

Dutch company Molecular Biology Systems (MBS), in collaboration with Amsterdam University Medical Center, and researchers from the Danish Rigshospitalet, has developed a fast typing method to trace monkeypox...

Global Health Cast Edition 8

Eighth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. Topics Covered: 00:00 Introduction 00:44 COVID19 Update 02:09 COVID19 Q&A 20:17 Main Messages Today 21:58 Cartoon of the...

Common viruses may be triggering the onset of Alzheimer’s disease

Alzheimer’s disease can begin almost imperceptibly, often masquerading in the early months or years as forgetfulness that is common in older age. What causes the disease remains largely a mystery. But...

Chinese scientists propose a new live-virus flu vaccine

Using attenuated, live viruses as vaccines is a promising strategy to reduce the impact of viral infectious diseases, such as influenza. Traditional live-attenuated virus vaccines have, however, often been...

Promising developments in pursuit to design pan-coronavirus vaccine

Researchers at the Francis Crick Institute have shown that a specific area of the SARS-CoV-2 spike protein is a promising target for a pan-coronavirus vaccine that could offer some protection against new virus...

Dreaming up new proteins, AI churns out possible medicines and vaccines

Computational biologist Jue Wang was already striving to develop an artificial intelligence (AI) to churn out candidate medicines when he had to rush his 2-year-old son to the hospital with a potentially...

Global Health Cast Edition 7

Seventh Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. Topics Covered: 00:00 Introduction 00:32 What we talk about today 00:49 COVID-19 update 05:58 Good Medical Language (GML)...

How vaccine-related fears affect the flu shot experience

A novel long-term study of how vaccine-related fears influence flu shot outcomes has found that these fears not only reduce vaccination, but also fuel symptoms of dizziness and lightheadedness at the time of...

A novel COVID-19 vaccine using modified bacterial DNA

Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, describe a different way to build a COVID-19 vaccine, one that would, in theory, remain effective against new...

New York detects vaccine-derived polio case

Health officials in New York  announced a vaccine-derived poliovirus type 2 case, which involves a person in Rockland County, prompting a vaccination push for the unimmunized and those who aren’t fully...

Ghana declares first-ever outbreak of Marburg virus disease

Ghana has announced the country’s first outbreak of Marburg virus disease. The Institute Pasteur in Dakar, Senegal, received samples from two patients from the southern Ashanti region of Ghana – both deceased...

Booster shots offset some Omicron immune evasion tactics

Although Omicron subvariants of the SARS-CoV-2 pandemic coronavirus have evolved to evade antibody responses from the primary COVID-19 vaccine series, a new laboratory study suggests current vaccine boosters...

Vaccine-induced immune response to omicron wanes substantially over time

Although COVID-19 booster vaccinations in adults elicit high levels of neutralizing antibodies against the Omicron variant of SARS-CoV-2, antibody levels decrease substantially within 3 months, according to...

Global Health Cast Edition 6

Sixth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. Topics Covered: 00:00 Introduction 0:29 What we talk about today 01:00 COVID-19 update 05:10 Do epidemics increase with...

Global Institute simplifies vaccine manufacturing for developing world

The concentration of biomanufacturing expertise in industrial nations left low- and middle-income countries with few ways to obtain the COVID-19 vaccines when they became available. That limited availability...

Vaccine-derived poliovirus Type 2 in London’s environmental samples

The UK Heath Security Agency (UKHSA) has found poliovirus in sewage samples collected from the London Beckton Sewage Treatment Works. As part of routine surveillance, these detections occurred when an...

Global Health Cast Edition 5

Fifth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. Topics Covered: 00:00 Introduction 00:42 COVID-19 update and news 10:25 Can bio-scans measure body oscillations predicting...

Study shows increase in COVID-19 vaccine acceptance around the world

COVID-19 vaccine acceptance increased 3.7% between 2020 and 2021, according to a new study from researchers at the CUNY Graduate School of Public Health and Health Policy (CUNY SPH), the Barcelona Institute...

Familiarity breeds exempt: why staph vaccines don’t work in humans

The sometimes-pathogenic bacteria has a long and intimate relationship with people, one that helps it fend off our immune response For the most part, the bacterium Staphylococcus aureus is common and harmless...

Global Health Cast Special 1: Monkeypox

First Special of the Global Health Cast presented by Prof. Schmitt and Dr. Florian Lienert. Download PDFs: Video Presentation / VacciTUTOR Chapter 58 – Smallpox and Monkeypox. Click here for more Global...

Mutations in virus causing monkeypox outbreak allow it to spread more easily

The strain of the virus in the current monkeypox outbreak in nonendemic countries likely diverged from the monkeypox virus that caused a 2018-19 Nigerian outbreak and has far more mutations than would be...

Scientists discover key to hepatitis A virus replication, show drug effectiveness

With no current treatments for hepatitis A, UNC School of Medicine scientists led by Stanley M. Lemon, MD, discovered how a protein and enzymes interact to allow hepatitis A virus to replicate, and they used a...

Global Health Cast Edition 4

Fourth Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. Topics Covered: 00:00 Introduction 00:35 Ticks don’t bite . . . as they do not have teeth 02:29 COVID-19 update and...

Some viruses make you smell tastier to mosquitoes

Zika and dengue fever viruses alter the scent of mice and humans they infect, researchers report in the June 30 issue of Cell. The altered scent attracts mosquitoes, which bite the host, drink their infected...

NIH scientists discover norovirus and other “stomach viruses” can spread through saliva

A class of viruses known to cause severe diarrheal diseases – including the one famous for widespread outbreaks on cruise ships – can grow in the salivary glands of mice and spread through their saliva...

How can a human challenge study help tackle the global impact of Salmonella?

Dr Malick Gibani explains how a human challenge study for non-typhoidal Salmonella can support vaccine development and protect vulnerable populations. Salmonella infection (salmonellosis) is a common disease...

Discovery of new Covid infection mechanism offers clue to SARS-CoV-2 leap to humans

One of the best-known aspects of the Covid-19 pandemic is that the virus ‘jumped’ into people from animals – perhaps bats or pangolins – in a process known as zoonotic transfer. What hasn’t been clear to...

Global Health Cast Edition 3

Third Edition of the Global Health Cast presented by Prof. Schmitt and Dr. Sanicas. Topics Covered: 00:00 Introduction 01:00 COVID-19 update and news 05:08 Can scientists/physicians make a difference in...

Down-regulating TAO2 prevents influenza from replicating in cells and could provide new target for antiviral therapies

A collaborative study from UT Southwestern scientists has identified a new function for a protein called TAO2 that appears to be key to inhibiting replication of the influenza virus, which sickens millions of...

Women more likely to have long COVID, different symptom profile

Women are significantly more likely than men to experience long COVID, with symptoms that follow a distinct clinical pattern, researchers reported. They said more efforts are needed to explore sex differences...

Understanding poor vaccine responses in individuals with weakened immune systems

When the COVID-19 vaccine first became available, people eagerly signed up for coveted slots to boost their antibodies against the virus that shut down much of the world. But not everyone who rolled up their...

Emory participating in trial to test mRNA HIV vaccine in humans

Emory University is participating in a Phase I clinical trial to evaluate the use of messenger RNA (mRNA) technology in HIV vaccines for the first time in humans. The trial, IAVI G002, was launched earlier...

Global Health Cast Edition 2

Topics Covered: 00:00 – Introduction 00:55 – Global COVID-19 situation: cases continue to decline 05:26 – AZD7442 – mAB for prevention of COVID-19 09:12 – Lack of Immune response to...

Going all the way: Scientists prove inhaled vaccines offer better protection than nasal sprays

Inhaled aerosol vaccines provide far better protection and stronger immunity than nasal sprays, McMaster scientists who compared respiratory vaccine-delivery systems have confirmed. While nasal sprays reach...

Monkeypox DNA hints virus has been spreading in people for years

Genome sequencing confirms that monkeypox cases outside Africa are all related and suggests the virus responsible may have been circulating in people since 2017 Rather than jumping to humans from animals...

Respiratory virus ‘kills 100,000 children under five’

Respiratory syncytial virus (RSV) is common cause of infections such as pneumonia. Most cases and deaths in young children occur in lower-income countries. Passive immunisation campaign urged for babies under...

As monkeypox threat grows, scientists debate best vaccine strategy

Favored shot is a seemingly safer smallpox vaccine, but efficacy remains unclear In 1959, German microbiologist Anton Mayr took a strain of vaccinia, a poxvirus used to inoculate against smallpox, and started...

Global Health Cast Edition 1

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