Critical Summary This article evaluates the cost-effectiveness of recently available respiratory syncytial virus (RSV) immunization options—nirsevimab (a long-acting monoclonal antibody) and the maternal RSVpreF...
Critical Summary The article by Malkin et al. presents the results of a phase 1, double-blind, randomized clinical trial evaluating the safety and immunogenicity of the rVSVΔG-LASV-GPC vaccine, a recombinant vesicular...
This narrative review by Gromer et al. provides a comprehensive synthesis of the long-observed but poorly characterized relationship between vaccine reactogenicity—short-term, inflammatory adverse events—and...
The 2025 study by Bui and colleagues reports on active, periodic surveillance of influenza A viruses (AIVs) at live bird markets (LBMs) in northern Vietnam — a region and context recognized as high-risk for zoonotic...
Marburg virus disease – Ethiopia (first recorded national outbreak) Marburg is a filovirus causing severe hemorrhagic fever with high case fatality; Ethiopia’s first outbreak in South Ethiopia Region has led to multiple...
This article presents a large-scale, longitudinal analysis of symptom patterns and the perceived disease burden of COVID-19 in the Netherlands, covering a 4.5-year period from November 2020 to April 2025. Using data...
Health Secretary Kennedy’s new policy direction on vaccines centers on undermining CDC assurances about vaccine safety (especially regarding autism and aluminum adjuvants) and on opening the door to schedule changes...
As one of the most prominent expert on polio, Jacob John and his colleagues write, vaccine safety is usually defined as the absence of serious adverse events in the vaccine recipient, yet the continued use of oral...
The first modern Lyme vaccine, LYMErix, was an OspA-based recombinant subunit vaccine that showed good efficacy and acceptable safety in phase III trials but ultimately failed due to a confluence of scientific...
For many years, the CDC’s vaccine-safety pages stated clearly that vaccines do not cause autism and used that phrase as a concise summary of a large evidence base. The earlier material explained that multiple large...