Potential HIV therapy prevents virus from multiplying after treatment is stopped

In alternative therapeutic approach to antiretroviral therapy may be effective in improving the condition of people with the HIV virus, scientists have said. They have developed new inhibitors called LEDGINs, which have shown promising results in slowing down the spread of the virus in cell cultures. The study, carried out by researchers from KU Leuven in Belgium, is published online in EbioMedecine. Although current available antiretroviral therapies can suppress the replication of the HIV virus and greatly improve patients’ health, they are unable to fully make it disappear from the human body. In this new research, the scientists investigated other types of inhibitors developed based on the properties of a cellular protein, known as LEDGF, which the HIV virus uses to attach itself to human cells and to subsequently spread in the body. The virus settles elsewhere This preliminary study was conducted in cell cultures. The researchers examined how a novel class of integration inhibitors,...