Tuberculosis – Global Health Press

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Vaccines and Vaccination (ViVa) – today and tomorrow looking at WHO’s Immunization Agenda 2030 (IA2030)

The trajectory of vaccine development in high‑income countries is approaching a turning point. With the licensure of respiratory syncytial virus (RSV) vaccines and monoclonal antibodies, most high‑incidence, high‑burden...

9 March, 2026

8 min read

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Oxford launches first human trial of aerosol vaccine delivery

The University of Oxford in partnership with the Coler Lab at Seattle Children’s Research Institute (SCRI) has begun a new clinical trial called TB045, which aims to test tuberculosis (TB) vaccine safety and the host...

27 March, 2025

3 min read

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Designing self-destructing bacteria to make effective tuberculosis vaccines

Working toward more effective tuberculosis (TB) vaccines, researchers at Weill Cornell Medicine have developed two strains of mycobacteria with “kill switches” that can be triggered to stop the bacteria...

26 February, 2025

4 min read

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Tuberculosis: gene editing could add new power to a 100-year-old vaccine

Tuberculosis dates back more than 9,000 years. It is the most infectious bacterial disease and in 2022 10.6 million people fell ill with it. Of these 23% occurred in Africa. The only vaccine against tuberculosis, the...

26 July, 2024

5 min read

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How a “neglected” immune response could lead to new pathways for developing TB vaccines

An “unconventional” immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB)...

17 July, 2024

2 min read

Latest Science

Breakthrough aerosol human infection model gives hope for future tuberculosis vaccine development

University of Oxford researchers have for the first time established a controlled human infection model for tuberculosis (TB) that infects people via the lungs – the way TB enters the body. The clinical trial, which...

16 April, 2024

3 min read

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Effects of MVA85A vaccine on tuberculosis

A new systematic review of animal studies testing a vaccine for tuberculosis raises questions about whether the studies provided sufficient evidence to move into trials of children. The new vaccine was a virus...

1 November, 2022

2 min read

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Tuberculosis vaccine passes safety test

The vaccine candidate VPM1002 shows its safety in a study with HIV- and non-HIV-exposed newborns No other infectious disease has killed more people than tuberculosis. Currently, only one vaccine is available to prevent...

8 August, 2022

5 min read

Latest Science

Why is the 100-year-old BCG vaccine so broadly protective in newborns?

The century-old Bacille Calmette-Guérin (BCG) vaccine against tuberculosis is one of the world’s oldest and most widely used vaccines, used to immunize 100 million newborns every year. Given in countries with endemic...

9 May, 2022

3 min read

Latest Science

New study identifies African “hotspot” for highly infectious diseases

A regional corner of Africa is a hotspot for cases of HIV, tuberculosis and malaria, prompting researchers to call for targeted health support rather than a national response. The new research, published in BMJ Global...

2 March, 2022

2 min read

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