After years of disappointments, the C. difficile vaccine field is quietly repositioning itself. While GSK has officially dropped its own toxoid candidate from the pipeline, at least two other toxin‑based approaches—one...
Clostridiodes difficile infection (CDI) remains a substantial public health issue, despite some recent reductions in healthcare-associated CDI.(1) Antimicrobial resistance is emerging(2), and relapse/recurrence is...
Immunosuppressed patients were found to exhibit impaired immune responses to treatment for Clostridioides difficile infection compared with patients who are not immunosuppressed, according to the results of a...