A new mRNA-based vaccine offers significant promise in both treating and preventing the highly contagious and notoriously difficult-to-treat Clostridioides difficile (C. difficile) infection, also known as C. diff. In...
Researchers from several U.S. institutions have developed an mRNA vaccine that has proven effective in protecting mice against intestinal Clostridioides difficile bacterial infections. In their paper published in...
In recent years, the focus on SARS-CoV-2 and mRNA-based vaccines has overshadowed work on other infectious diseases and vaccine approaches. However, attention is now shifting, as experts from three vaccine-focused...
An experimental mRNA-based vaccine against all 20 known subtypes of influenza virus provided broad protection from otherwise lethal flu strains in initial tests, and thus might serve one day as a general preventative...
An experimental HIV vaccine based on mRNA—the same platform technology used in two highly effective COVID-19 vaccines—shows promise in mice and non-human primates, according to scientists at the National Institute of...
A top Pfizer executive says the company is hopeful that booster shots will provide sufficient protection against the Omicron variant — but has already envisioned a timeline for the development of a new vaccine if that’s...
British physician Edward Jenner created the world’s first vaccine in 1796, against smallpox, by injecting a patient with pus from the sores of a milkmaid who had contracted a biologically related virus from cows. And...
Of all the Covid-19 vaccine candidates making their way through the regulatory pipeline, the two from Pfizer/BioNTech and Moderna are some of the most exciting. In addition to having reported efficacies of 90% of more...