Molecular clamping in vaccine development refers to a technology that uses a specially designed polypeptide (the “molecular clamp”) to stabilize viral proteins, particularly their pre-fusion conformations...
Europe is pursuing a path similar to the one described for the U.S., leveraging real-world data (RWD) and artificial intelligence (AI) to advance healthcare research—but there are important distinctions shaped by the...
References Davis HE, McCorkell L, Vogel JM, Topol EJ. Long COVID: major findings, mechanisms and recommendations. Nat Rev Microbiol. 2023;21(8):438-451. doi:10.1038/s41579-022-00846-2 Li X, Mi Z, Liu Z, Rong P. SARS-CoV...
References World Health Organization. A clinical case definition of post-COVID-19 condition by a Delphi consensus, 6 October 2021. National Institute for Health and Care Excellence (NICE), Royal College of General...
While some infectious diseases, such as measles, typically confer lifelong immunity after a single natural infection, many others do not. For these diseases, natural infection may only provide temporary protection, and...
The European Vaccines Hub for Pandemic Readiness (EVH) is a newly established, EU-funded public-private partnership led by the Sclavo Vaccines Association (Siena, Italy), pooling 11 major beneficiaries and 13 affiliated...
Clostridiodes difficile infection (CDI) remains a substantial public health issue, despite some recent reductions in healthcare-associated CDI.(1) Antimicrobial resistance is emerging(2), and relapse/recurrence is...
Certain groups are at increased risk for severe disease courses, complications, hospitalization, or death from influenza. The main risk groups include: Older adults: Especially those aged 60 years and above. Young...
Still today, 90% of influenza vaccine doses produced annually are egg-based. They are cheap and have a well-documented excellent safety profile. However, in case of an influenza pandemic with a “bird-flu-strain”, there...
In Asia, major producers are scaling up both legacy and next-generation vaccine capacity. India’s Serum Institute, the world’s largest vaccine manufacturer, recently announced expanded partnerships with African...