In short: Classic vaccines have picked most of the low-hanging fruit: stable-antigen pathogens tamed by robust neutralizing antibodies, leaving the real fun to TB, HIV and other shape-shifters that demand sophisticated...
The Influenza vaccination After Myocardial Infarction (IAMI) trial is a pivotal, multicenter, randomized, double-blind, placebo-controlled study designed to assess the clinical benefit and safety of influenza...
Download Infographic Overview HPV (Human Papillomavirus) is extremely common worldwide and is mainly transmitted through sexual contact; most people are infected shortly after the onset of sexual activity. There are...
Reference: Zar HJ, Simões EAF, Madhi SA, et al. Clesrovimab for prevention of RSV disease in healthy infants. N Engl J Med. 2025;393(13):1292-1303. Background and Study Rationale Clesrovimab is engineered as a long...
References Davis HE, McCorkell L, Vogel JM, Topol EJ. Long COVID: major findings, mechanisms and recommendations. Nat Rev Microbiol. 2023;21(8):438-451. doi:10.1038/s41579-022-00846-2 Li X, Mi Z, Liu Z, Rong P. SARS-CoV...
The Independent Task Force on COVID-19 and other Pandemics announced that their report “Pandemic Origins and a One Health Approach to Preparedness and Prevention: Solutions Based on SARS-CoV-2 and Other RNA Viruses” has...
Crises of infectious diseases are becoming more common. The world should be better prepared. One of the sobering lessons of the Ebola crisis was how ill-prepared the world was for such a deadly disease. It is terrifying...
Live attenuated (weakened) viral vaccines are considered safe so long as their “reversal” to a virulent (or disease-causing) virus is prevented. A study published on October 29th in PLOS Pathogens reports on...
We’re removing the doorway that HIV uses to get into cells” Natural immunity is the most reliable way to protect yourself from viruses, bacteria and parasites. And the best way to acquire such immunity, in...
A broader base of funders is needed to sustain support for HIV prevention research, which continues to make breakthroughs that could help to end the AIDS epidemic, according to a report released on Saturday. The report...