DNA research seeks vaccine for Malaria

U.S. researchers say a vaccine based on genetically engineered DNA could induce an immune response in humans to protect against malaria parasite infection. The PATH Malaria Vaccine Initiative U.S. researchers say a vaccine based on genetically engineered DNA could induce an immune response in humans to protect against malaria parasite infection. and Inovio Pharmaceuticals Inc. announced a partnership to combine DNA research aimed at developing malaria vaccines with an innovative vaccine delivery technology called electroporation. Electroporation uses controlled electrical impulses to create temporary pores in a cell membrane, allowing uptake of the synthetic DNA that then causes the cell to produce proteins mimicking the presence of the malaria pathogen. The goal is to induce an immune response that provides protection against malaria, a deadly disease that still kills more than 500,000 children under age 5 every year, a PATH MVI release reported. “We are excited to bring this innovative delivery technology into clinical...