Cure for SARS virus comes closer to reality

Researchers have uncovered components of the SARS coronavirus that allow it to take over host cells in order to multiply, paving way for development of therapies for the deadly virus. The virus triggered a major outbreak of severe acute respiratory syndrome in 2002-03, researchers said. This insight is critical for a full understanding of any outbreaks caused by such viruses and may prove beneficial in the development of therapies not only for human coronavirus infections but for other pathogenic illnesses as well. Megan Angelini, a graduate student in Professor Michael Buchmeier’s laboratory in the Department of Molecular Biology & Biochemistry at University of California Irvine, and colleagues found that three proteins in the SARS coronavirus – nsp3, nsp4 and nsp6 – have the ability to hijack a host cell’s internal membranes and utilise them to make more virus. “Understanding how the virus uses the host cell to reproduce itself could lead to potential therapies...