Research reveals components of Sinbis virus ribonucleoproteins

Arthropod-borne viruses (arboviruses), belonging to the genus alphavirus, commonly infect human beings. Some of the examples of arboviruses are Ross River virus (RRV), Venezuelan equine encephalitis virus (VEEV), Chikungunya (CHIKV), Semliki forest virus (SFV), and Sindbis virus (SINV). Background Previous studies have shown that arboviruses grow in the salivary glands of mosquitoes from the Aedes family (e.g., Aedes aegypti and Aedes albopictus). These mosquitoes act as a vector and transmit the virus to the human host through their bites. According to recent reports, these vectors are increasing in number due to global warming and international trade. These events raise concerns regarding the emergence of arboviral outbreaks and epidemics around the world. Hence, it is essential to further our understanding of the host-virus interactions associated with alphavirus infection to identify potential targets crucial for the development of effective therapeutics. Characteristic features of alphaviruses Alphaviruses are positive-sense, single-stranded RNA genomes of size around 11kb. The viral genomes...