Global Health Press

Study suggests a different design for staph vaccine to tackle antibiotic resistance

Staphylococcus aureus is a Gram-positive, round-shaped bacterium that is most commonly isolated from all forms of osteomyelitis.

Staph bacteria are one of the many bacteria that seem to have become drug-resistant and is a matter of concern for medical professionals and healthcare since the bacteria is a cause behind many skin conditions. Various attempts to create a vaccine against the bacteria did not yield fruitful results.

However, researchers from the Washington University School of Medicine in St. Louis have tried to explain why the past vaccines may have failed and have also proposed a new approach to the vaccine design. Under the strategy, the researchers propose the stimulation during or within the first few days after birth, of untapped immune cells, and immunization against staphs.

The findings of the study were published in the Journal of Clinical Investigation, and it was found that in the mice model, T cells play a critical role in protecting against the staphylococcus bacteria. Since most vaccines rely on stimulating other types of immune cells, which produce antibodies to attack the germs which cause the disease, they remain ineffective in killing the staph bacteria.

Therefore, researchers suggest that a robust T cell response is what is required to protect against staph infections.


Notify of
Inline Feedbacks
View all comments