Breakthrough in respiratory virus prevention and treatment: researchers develop NanoSTING nasal spray and pan-coronavirus vaccine

A team of researchers, led by the University of Houston (UH), has discovered two new ways of preventing and treating respiratory viruses. In back-to-back papers in Nature Communications, the team — from the lab of Navin Varadarajan, M.D. Anderson Professor of William A. Brookshire Chemical and Biomolecular Engineering – reports the development and validation of NanoSTING, a nasal spray, as a broad-spectrum immune activator for controlling infection against multiple respiratory viruses; and the development of NanoSTING-SN, a pan-coronavirus nasal vaccine, that can protect against infection and disease by all members of the coronavirus family. NanoSTING Therapeutic’s Highlights NanoSTING, a nasal spray, can prevent multiple respiratory viruses by activating the immune system and preventing infection from viruses. It can also protect against SARS-CoV-2 reinfection. A single intranasal dose of the NanoSTING has proven effective against strains of SARS-CoV-2 and the flu virus. NanoSTING is complementary to vaccines and enables cells to be in a heightened...