Ebola virus disease – Democratic Republic of the Congo

The World Health Organization provides a detailed report on the Ebola virus disease (EVD) outbreak that occurred in the Bulape Health Zone of Kasai Province, Democratic Republic of the Congo (DRC), in 2025. The Ministry of Health officially declared the outbreak over on 1 December 2025, following 42 days without new cases. This comprehensive update outlines the course of the outbreak, the public health response, outcomes, and ongoing risks, while offering important insights into both the strengths and limitations of outbreak control efforts in resource-limited settings. The outbreak was first detected on 4 September 2025 and ultimately resulted in 64 total cases, including 53 laboratory-confirmed and 11 probable infections. With 45 associated deaths, the outbreak had a high case fatality ratio of approximately 70%, consistent with the severity typically observed in Zaire ebolavirus outbreaks. Transmission occurred across six health areas—Bambalaie, Bulape, Bulape Com, Dikolo, Ingongo, and Mpianga—with the majority of infections...