As of September 15, 2026, the largest acute international outbreak is Bundibugyo Ebola virus disease in the Democratic Republic of the Congo (DRC), which continues to expand rapidly. Other active priorities include mpox, seasonal arboviral threats in Europe, dengue and measles in the Americas, and multiple ongoing foodborne outbreak investigations in the United States. Uganda’s related Ebola outbreak and Guinea’s Marburg outbreak have been declared over. Africa and global emergencies Bundibugyo Ebola virus disease — Democratic Republic of the Congo: The DRC outbreak remains active and continues to grow. CDC reported 7,200 confirmed cases and 3,475 deaths as of September 12, up from 6,757 confirmed cases and 3,267 deaths as of September 7. WHO and ECDC reporting indicate ongoing transmission centered in affected DRC provinces, requiring intensified case isolation and treatment, laboratory confirmation, contact tracing, safe and dignified burials, infection prevention and control, community engagement, and cross-border surveillance. Bundibugyo Ebola virus disease...
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